Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 9/20 | 0.52 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.52 |
| ▸ | CTSK | P43235 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476675 | 0.84 | KDM4E (0.43) | GRIN2BHTR7CHRM4DRD2HTR2A | |
| SCHEMBL21883968 | 0.77 | GRIN2B (0.70) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| SCHEMBL29756361 | 0.77 | GRIN2B (0.70) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| SCHEMBL8322968 | 0.77 | GRIN2B (0.70) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| SCHEMBL10924004 | 0.74 | GRIN2B (0.70) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| SCHEMBL5532807 | 0.74 | GRIN2B (0.70) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| SCHEMBL34463426 | 0.74 | GRIN2B (0.65) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| SCHEMBL18669422 | 0.74 | GRIN2B (0.65) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| Xestoamine SCHEMBL2271935 | 0.74 | GRIN2B (0.65) | GRIN2BHTR7CHRM4CTSKDRD2 | |
| Xestoamine SCHEMBL6087465 | 0.73 | GRIN2B (0.64) | GRIN2BHTR7CHRM4CTSKDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2476680-B1 | (1-Azinone)-Substituted Pyridoindoles | ALBANY MOLECULAR RES INC (US) | 2014-08-27 | — | — | EP | disclosed |