Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.70 |
| ▸ | HTR7 | P34969 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.60 |
| ▸ | CTSK | P43235 | 1/20 | 0.60 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 3/20 | 0.58 |
| ▸ | HTR2A | P28223 | 3/20 | 0.54 |
| ▸ | HTR2C | P28335 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29756361 | 0.85 | GRIN2B (0.70) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL10924004 | 0.85 | GRIN2B (0.70) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21883968 | 0.85 | GRIN2B (0.70) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL8322968 | 0.85 | GRIN2B (0.70) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL3246180 | 0.83 | GRIN2B (0.67) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| Fenharmane SCHEMBL9695673 | 0.82 | GRIN2B (1.00) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| Fenharmane SCHEMBL9696484 | 0.81 | GRIN2B (0.97) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL34463426 | 0.81 | GRIN2B (0.65) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL18669422 | 0.81 | GRIN2B (0.65) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 | |
| Xestoamine SCHEMBL2271935 | 0.81 | GRIN2B (0.65) | GRIN2BHTR7CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007147819-A1 | 3H,11H-OXAZOLO[3',4':1,2]PYRIDO[3,4-B]INDOLE DERIVATIVES AND THERAPEUTIC USE THEREOF | FOURTILLAN (FR) | 2007-12-27 | — | — | WO | disclosed |
| US-4625032-A | LIVER DISORDERS | TANABE SEIYAKU CO., LTD. (JP) | 1986-11-25 | — | — | US | disclosed |
| EP-0165017-A2 | Novel tetrahydro-B-carboline derivative and processes for preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1985-12-18 | — | — | EP | disclosed |