SCHEMBL8322968

SCHEMBL8322968

CCC1NCCc2c1[nH]c1ccccc21

nearest known ligand 0.70

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
GRIN2B Q13224 1/20 0.70
HTR2A P28223 5/20 0.68
HTR2C P28335 5/20 0.68
HTR7 P34969 8/20 0.63
CHRM4 P08173 5/20 0.63
CYP3A4 P08684 1/20 0.60
CYP2D6 P10635 1/20 0.60
CYP2C19 P33261 1/20 0.60
CTSK P43235 1/20 0.60
DRD2 P14416 3/20 0.59
MAPKAPK2 P49137 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21883968 1.00 GRIN2B (0.70) GRIN2BHTR2AHTR2CHTR7CHRM4
SCHEMBL29756361 1.00 GRIN2B (0.70) GRIN2BHTR2AHTR2CHTR7CHRM4
SCHEMBL5532807 0.85 GRIN2B (0.70) GRIN2BHTR2AHTR2CHTR7CHRM4
SCHEMBL10924004 0.85 GRIN2B (0.70) GRIN2BHTR2AHTR2CHTR7CHRM4
SCHEMBL14892998 0.85 GRIN2B (0.62) GRIN2BHTR2AHTR2CHTR7CHRM4
SCHEMBL18669422 0.84 GRIN2B (0.65) GRIN2BHTR2AHTR2CHTR7CHRM4
Xestoamine SCHEMBL2271935 0.84 GRIN2B (0.65) GRIN2BHTR2AHTR2CHTR7CHRM4
Xestoamine SCHEMBL6087465 0.83 GRIN2B (0.64) GRIN2BHTR2AHTR2CHTR7CHRM4
Fenharmane SCHEMBL9695673 0.82 GRIN2B (1.00) GRIN2BHTR2AHTR2CHTR7CHRM4
SCHEMBL24506125 0.82 GRIN2B (0.62) GRIN2BHTR2AHTR2CHTR7CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630512-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2026-05-19 US disclosed
EP-3600451-B1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2025-12-24 EP disclosed
US-12202799-B2 Agents for differentiating stem cells and treating cancer MINERVA BIOTECHNOLOGIES CORPORATION (US) 2025-01-21 US disclosed
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2024-12-12 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION 2022-08-04 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MINERVA BIOTECHNOLOGIES CORPORATION 2021-09-30 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORP (US) 2021-03-25 US disclosed
EP-3600451-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER Minerva Biotechnologies Corporation (US) 2020-02-05 EP disclosed
EP-3535263-A1 SUBSTITUTED PYRIDO[3,4-B]INDOLES FOR THE TREATMENT OF CARTILAGE DISORDERS Sanofi (FR) 2019-09-11 EP disclosed
WO-2018183654-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MINERVA BIOTECHNOLOGIES CORPORATION (US) 2018-10-04 WO disclosed
WO-2004113336-A1 CARBOLINE AND BETACARBOLINE DERIVATIVES FOR USE AS HDAC ENZYME INHIBITORS CHROMA THERAPEUTICS LIMITED (GB) 2004-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210299109-A1 AGENTS FOR TREATING CANCER AND METHODS FOR IDENTIFYING SAID AGENTS MCL1, CD44, EPCAM GRIN2B 4259/4885HTR2A 4615/4885HTR2C 4566/4885
US-12202799-B2 Agents for differentiating stem cells and treating cancer MCL1, CD44, CRABP2 GRIN2B 3448/4885HTR2A 4440/4885HTR2C 4453/4885
US-20210087143-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 GRIN2B 3448/4885HTR2A 4440/4885HTR2C 4453/4885
US-12630512-B2 Agents for differentiating stem cells and treating cancer MCL1, POU2F1, NES GRIN2B 3235/4885HTR2A 3307/4885HTR2C 1923/4885
US-20240409515-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 GRIN2B 3448/4885HTR2A 4440/4885HTR2C 4453/4885
US-20220242823-A1 AGENTS FOR DIFFERENTIATING STEM CELLS AND TREATING CANCER MCL1, CD44, CRABP2 GRIN2B 3448/4885HTR2A 4440/4885HTR2C 4453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.