SCHEMBL15977602

SCHEMBL15977602

c1cncc(-c2ccc(-c3ccc4c(-c5cc6ccccc6c6ccccc56)c5ccccc5c(-c5cccc6ccccc56)c4c3)nc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 6/20 0.52
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
GPR84 Q9NQS5 1/20 0.40
CYP2A6 P11509 2/20 0.40
CYP11B2 P19099 5/20 0.39
CYP17A1 P05093 1/20 0.39
CYP19A1 P11511 1/20 0.39
DHODH Q02127 1/20 0.38
CCNT1 O60563 2/20 0.37
CCNA2 P20248 2/20 0.37
CDK2 P24941 2/20 0.37
CDK9 P50750 2/20 0.37
CYP2C9 P11712 2/20 0.36
PDPK1 O15530 1/20 0.36
CYP3A4 P08684 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977922 0.97 CYP11B1 (0.51) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL15977924 0.94 KDM4E (0.46) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL15977536 0.94 CYP11B1 (0.58) CYP11B1GPR84CYP2A6CYP11B2CYP17A1
SCHEMBL15977740 0.91 CYP11B1 (0.54) CYP11B1GPR84CYP2A6CYP11B2CYP17A1
SCHEMBL15977826 0.91 CYP11B1 (0.54) CYP11B1GPR84CYP2A6CYP11B2CYP17A1
SCHEMBL15977579 0.91 CYP11B1 (0.46) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL15977580 0.91 CYP11B1 (0.57) CYP11B1GPR84CYP2A6CYP11B2CYP17A1
SCHEMBL15977845 0.90 CYP11B1 (0.39) CYP11B1KDM4EALDH1A1MAPTHPGD
SCHEMBL15977584 0.88 CYP11B1 (0.53) CYP11B1GPR84CYP2A6CYP11B2CYP17A1
SCHEMBL15977586 0.88 CYP11B1 (0.53) CYP11B1GPR84CYP2A6CYP11B2CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 CYP11B1 1241/4885KDM4E 3416/4885ALDH1A1 196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.