SCHEMBL15977802

SCHEMBL15977802

c1ccc(-c2cc(-c3ccccc3)cc(-c3c4ccccc4c(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)c4cc(-c5ncccn5)ccc34)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 3/20 0.38
DYRK1A Q13627 1/20 0.38
RAB9A P51151 4/20 0.37
NPC1 O15118 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
NFKB1 P19838 2/20 0.37
NFKB2 Q00653 2/20 0.37
RELA Q04206 2/20 0.37
GP6 Q9HCN6 1/20 0.37
PIK3CA P42336 1/20 0.36
CYP2A6 P11509 1/20 0.35
MAP4K4 O95819 1/20 0.35
ALK Q9UM73 1/20 0.35
EGFR P00533 1/20 0.34
MKNK1 Q9BUB5 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PIK3CD O00329 1/20 0.33
PIP5K1C O60331 1/20 0.33
PI4KA P42356 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15977564 0.93 CLK4 (0.40) CLK4DYRK1ARAB9ANPC1SMN1; SMN2
SCHEMBL10301024 0.91 CLK4 (0.41) CLK4DYRK1ARAB9ANPC1SMN1; SMN2
SCHEMBL10301065 0.90 CLK4 (0.42) CLK4DYRK1ARAB9ANPC1SMN1; SMN2
SCHEMBL15977844 0.89 NPC1 (0.53) RAB9ANPC1SMN1; SMN2NFKB1NFKB2
SCHEMBL15977696 0.88 NPC1 (0.42) CLK4RAB9ANPC1SMN1; SMN2NFKB1
SCHEMBL15977705 0.88 NPC1 (0.42) CLK4RAB9ANPC1SMN1; SMN2NFKB1
SCHEMBL15977778 0.88 NPC1 (0.42) CLK4RAB9ANPC1SMN1; SMN2NFKB1
SCHEMBL15977891 0.88 NPC1 (0.42) CLK4RAB9ANPC1SMN1; SMN2NFKB1
SCHEMBL10301053 0.86 NPC1 (0.44) CLK4DYRK1ARAB9ANPC1SMN1; SMN2
SCHEMBL10301140 0.85 MEN1 (0.43) GP6MEN1KMT2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 CLK4 1690/4885DYRK1A 4414/4885RAB9A 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.