Sugi Predict

Sugi Predict / Compounds / SCHEMBL15977909

SCHEMBL15977909

SCHEMBL15977909

CC1(C)c2ccc(-c3ccc4c(-c5ccccc5)c5ccccc5c(-c5ccccc5)c4c3)cc2-c2cc(-c3ccccn3)ccc21

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDK2 Q15119 1/20 0.38
▸ TNKS O95271 2/20 0.36
▸ DHODH Q02127 1/20 0.36
▸ PRMT5 O14744 2/20 0.36
▸ WDR77 Q9BQA1 1/20 0.36
▸ BRD4 O60885 1/20 0.34
▸ KDR P35968 1/20 0.34
▸ TSHR P16473 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ METAP2 P50579 1/20 0.34
▸ CYP2A6 P11509 1/20 0.33
▸ BACE1 P56817 1/20 0.33
▸ PIM1 P11309 1/20 0.33
▸ PIM3 Q86V86 1/20 0.33
▸ RET P07949 1/20 0.33
▸ RIPK1 Q13546 1/20 0.33
▸ RIPK3 Q9Y572 1/20 0.33
▸ PKMYT1 Q99640 1/20 0.32
▸ AXL P30530 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13487507 0.90 PDK2 (0.39) PDK2TNKSDHODHTSHRMAPK1
SCHEMBL13487549 0.89 PDK2 (0.39) PDK2TNKSDHODHPRMT5WDR77
SCHEMBL13149582 0.86 PDK2 (0.40) PDK2TNKSDHODHPRMT5WDR77
SCHEMBL13487759 0.86 PDK2 (0.42) PDK2DHODHPRMT5WDR77BRD4
SCHEMBL13487774 0.85 PDK2 (0.42) PDK2DHODHPRMT5WDR77BRD4
SCHEMBL10300903 0.84 DHODH (0.46) PDK2DHODHPRMT5WDR77KDR
SCHEMBL15977733 0.83 PDK2 (0.43) PDK2TNKSDHODHPRMT5WDR77
SCHEMBL13487898 0.83 PDK2 (0.42) PDK2DHODHBRD4TSHRMAPK1
SCHEMBL13487929 0.83 PDK2 (0.42) PDK2DHODHPRMT5WDR77BRD4
SCHEMBL10300931 0.83 PRMT5 (0.46) PDK2DHODHPRMT5WDR77KDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS IDEMITSU KOSAN CO.,LTD. (JP) 2022-12-29 — — US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 — — US disclosed
US-9559311-B2 Anthracene derivative, organic-electroluminescence-device material, organic electroluminescence device, and electronic equipment IDEMITSU KOSAN CO., LTD. (JP) 2017-01-31 — — US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 — — US disclosed
US-20140239273-A1 ANTHRACENE DERIVATIVE, ORGANIC-ELECTROLUMINESCENCE-DEVICE MATERIAL, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC EQUIPMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220416178-A1 COMPOSITION, ORGANIC ELECTROLUMINESCENCE DEVICE, AND ELECTRONIC APPARATUS PIEZO1, TMEM109, SLC39A14 PDK2 924/4885TNKS 3252/4885DHODH 3858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.