Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | TERT | O14746 | 3/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | BLM | P54132 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | FABP4 | P15090 | 2/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GMNN | O75496 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8775413 | 0.84 | FFAR1 (0.56) | EPHX2FFAR1FFAR4TERTPTPN1 | |
| SCHEMBL26305292 | 0.80 | CNR1 (0.59) | EPHX2FFAR1FFAR4TERTPTPN1 | |
| SCHEMBL9396720 | 0.79 | TERT (0.51) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL6532069 | 0.79 | EPHX2 (0.54) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL6533881 | 0.79 | EPHX2 (0.54) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL8925859 | 0.79 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL18240158 | 0.79 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL540326 | 0.79 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL79558 | 0.79 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD | |
| SCHEMBL8004893 | 0.79 | EPHX2 (0.64) | EPHX2TERTPTPN1PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919310-B2 | Expression vector comprising nucleotide sequences coding radiosensitizing or radioprotecting factors for use in prevention and treatment of cell proliferative disorders | THE UNIVERSITY OF CHICAGO (US) | 2011-04-05 | — | — | US | disclosed |
| US-7592317-B1 | Constitutive gene expression in conjuction with ionizing radiation | THE UNIVERSITY OF CHICAGO (US) | 2009-09-22 | — | — | US | disclosed |
| US-20080118471-A1 | CONSTITUTIVE GENE EXPRESSION IN CONJUNCTION WITH IONIZING RADIATION | DANA-FARBER CANCER INSTITUTE (US) | 2008-05-22 | — | — | US | disclosed |
| WO-1997008184-A1 | METHODS AND COMPOSITIONS INCLUDING DNA DAMAGING AGENTS AND TYROSINE KINASE INHIBITORS OR ACTIVATORS | ARCH DEVELOPMENT CORPORATION (US) | 1997-03-06 | — | — | WO | disclosed |