SCHEMBL540326

SCHEMBL540326

CCCCCCCC/C=C\CCCCCCCC(=O)N(C)C(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.64
TERT O14746 3/20 0.63
PTPN1 P18031 3/20 0.63
PPARG P37231 3/20 0.63
PPARD Q03181 3/20 0.63
PPARA Q07869 3/20 0.63
CYP1A2 P05177 2/20 0.63
MAPT P10636 2/20 0.63
CYP2C19 P33261 2/20 0.63
BLM P54132 2/20 0.63
HSD17B10 Q99714 2/20 0.63
FABP4 P15090 2/20 0.63
FAAH O00519 2/20 0.63
KMT2A Q03164 2/20 0.63
GMNN O75496 1/20 0.63
USP2 O75604 1/20 0.63
LMNA P02545 1/20 0.63
POLB P06746 1/20 0.63
CYP2C9 P11712 1/20 0.63
ALOX15 P16050 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564586 1.00 EPHX2 (0.64) EPHX2TERTPTPN1PPARGPPARD
Bromide SCHEMBL17743564 0.98 EPHX2 (0.62) EPHX2TERTPTPN1PPARGPPARD
Hydrochloric Acid SCHEMBL565816 0.98 EPHX2 (0.62) EPHX2TERTPTPN1PPARGPPARD
Fluoride SCHEMBL17743568 0.98 EPHX2 (0.62) EPHX2TERTPTPN1PPARGPPARD
Iodide SCHEMBL21048369 0.98 EPHX2 (0.62) EPHX2TERTPTPN1PPARGPPARD
Iodide SCHEMBL17743505 0.98 EPHX2 (0.62) EPHX2TERTPTPN1PPARGPPARD
Stearic Acid SCHEMBL6898220 0.93 PPARG (0.77) EPHX2TERTPTPN1PPARGPPARD
Sulfuric Acid SCHEMBL17743519 0.93 EPHX2 (0.57) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL10793545 0.91 EPHX2 (0.59) EPHX2TERTPTPN1PPARGPPARD
SCHEMBL10793538 0.91 EPHX2 (0.59) EPHX2TERTPTPN1PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2414322-B1 POLYAMINE DERIVATIVES EGEN INC (US) 2022-09-14 EP disclosed
CN-104922676-B Polyamine derivatives CLSN实验室股份有限公司 2019-03-12 CN disclosed
CN-102438978-B polyamine derivatives CLSN实验室股份有限公司 2017-02-22 CN disclosed
US-9254334-B2 Polyamine derivatives CLSN LABORATORIES, INC. (US) 2016-02-09 US disclosed
CN-104922676-A POLYAMINE DERIVATIVES CLSN LAB INC 2015-09-23 CN disclosed
US-20150099000-A1 Polyamine Derivatives CLSN LABORATORIES, INC. (US) 2015-04-09 US disclosed
US-8932638-B2 Polyamine derivatives CLSN LABORATORIES, INC. (US) 2015-01-13 US disclosed
US-8900621-B2 Polyamine derivatives CLSN LABORATORIES, INC. (US) 2014-12-02 US disclosed
US-20140050775-A1 Polyamine Derivatives EGEN, INC. (US) 2014-02-20 US disclosed
US-20130251809-A1 Polyamine Derivatives EGEN, INC. (US) 2013-09-26 US disclosed
US-8460696-B2 Polyamine derivatives EGEN, INC. (US) 2013-06-11 US disclosed
CN-102438978-A Polyamine derivatives EGEN INC 2012-05-02 CN disclosed
EP-2414322-A2 POLYAMINE DERIVATIVES Egen, Inc. (US) 2012-02-08 EP disclosed
US-20100260817-A1 Polyamine Derivatives EGEN, INC. 2010-10-14 US disclosed
WO-2010108108-A2 POLYAMINE DERIVATIVES EGEN, INC. (US) 2010-09-23 WO disclosed
EP-1505109-B1 AGENT FOR INHIBITING MIGRATION OF ODOR AND TASTE GENERATED FROM DIACETAL, DIACETAL COMPOSITION CONTAINING THE AGENT FOR INHIBITING ODOR AND TASTE MIGRATION, NUCLEATING AGENT FOR POLYOLEFIN COMPRISING THE COMPOSITION, AND POLYOLEFIN RESIN COMPOSITION AND MOLDED OBJECT EACH CONTAINING THE NUCLEATING AGENT NEW JAPAN CHEM CO LTD (JP) 2010-09-15 EP disclosed
US-20050171230-A1 Agent for suppressing transfer of odor and taste originating from a diacetal a diacetal composition comprising the agent for suppressing transfer of odor and taste a polyolefin nucleating agent comprising the composition a polyolefin resin composition and a molded product comprising the nucleating agent NEW JAPAN CHEMICAL CO., LTD. (JP) 2005-08-04 US disclosed
EP-1505109-A1 AGENT FOR INHIBITING MIGRATION OF ODOR AND TASTE GENERATED FROM DIACETAL, DIACETAL COMPOSITION CONTAINING THE AGENT FOR INHIBITING ODOR AND TASTE MIGRATION, NUCLEATING AGENT FOR POLYOLEFIN COMPRISING THE COMPOSITION, AND POLYOLEFIN RESIN COMPOSITION AND MOLDED OBJECT EACH CONTAINING THE NUCLEATING A NEW JAPAN CHEMICAL CO.,LTD. (JP) 2005-02-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130251809-A1 Polyamine Derivatives SRM, SMS, SGMS2 EPHX2 2183/4885TERT 3716/4885PTPN1 4719/4885
US-20150099000-A1 Polyamine Derivatives SRM, SMS, SGMS2 EPHX2 2183/4885TERT 3716/4885PTPN1 4719/4885
US-20100260817-A1 Polyamine Derivatives SRM, SMS, SGMS2 EPHX2 2183/4885TERT 3716/4885PTPN1 4719/4885
US-20140050775-A1 Polyamine Derivatives SRM, SMS, SGMS2 EPHX2 2183/4885TERT 3716/4885PTPN1 4719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.