SCHEMBL15980417

SCHEMBL15980417

CN(C)CCN(C)C(=O)[C@@H]1C2CCC(C2)[C@@H]1C(=O)C(C)(C)C

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FPR3 P25089 1/20 0.32
▸ FPR2 P25090 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16521982 1.00 FPR3 (0.32) FPR3FPR2
SCHEMBL47619 0.78 FPR3 (0.36) FPR3FPR2
SCHEMBL47606 0.78 FPR3 (0.36) FPR3FPR2
SCHEMBL25139918 0.77 TAAR1 (0.40) FPR3FPR2
SCHEMBL25139914 0.77 TAAR1 (0.40) FPR3FPR2
SCHEMBL18566580 0.72 ADORA1 (0.36) —
SCHEMBL47599 0.72 ADORA1 (0.36) —
SCHEMBL47603 0.72 ADORA1 (0.36) —
SCHEMBL99323 0.72 ADORA1 (0.36) —
SCHEMBL14175046 0.67 ADORA1 (0.43) FPR3FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150057221-A1 PRODRUG COMPRISING A DRUG LINKER CONJUGATE ASCENDIS PHARMA AS (DK) 2015-02-26 — — US disclosed
US-20140243254-A1 Polymeric Hyperbranched Carrier-Linked Prodrugs ASCENDIS PHARMA A/S (DK) 2014-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150057221-A1 PRODRUG COMPRISING A DRUG LINKER CONJUGATE H1-0, H1-3, H1-2 FPR3 1252/4885FPR2 2195/4885
US-20140243254-A1 Polymeric Hyperbranched Carrier-Linked Prodrugs P4HA1, CYP8B1, PAH FPR3 1990/4885FPR2 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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