Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | XIAP | P98170 | 1/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.55 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylalanine Amide SCHEMBL16001480 | 1.00 | ALPI (0.60) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL3439692 | 0.86 | SLC7A5 (0.74) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Dl-Phenylalanine SCHEMBL2939606 | 0.86 | SLC7A5 (0.74) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL353251 | 0.86 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL11349868 | 0.86 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL244302 | 0.86 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL244303 | 0.86 | SLC7A5 (0.73) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL23002157 | 0.84 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL7613303 | 0.84 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 | |
| Phenylalanine Amide SCHEMBL11569548 | 0.84 | SLC7A5 (0.70) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9453063-B2 | Hybrid polypeptides with selectable properties | AMYLIN PHARMACEUTICALS, LLC. (US) | 2016-09-27 | — | — | US | disclosed |
| US-20140249299-A1 | HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES | ASTRAZENECA PHARMACEUTICALS LP (US) | 2014-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249299-A1 | HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES | IAPP, IGFBP1, PGF | ALPI 2908/4885PKM 3000/4885PTGS1 1505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.