IGFBP1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL10923514	0.47	2/20
SCHEMBL29360098	0.47	2/20
SCHEMBL21979549	0.46	2/20
SCHEMBL30514356	0.46	2/20
SCHEMBL5825926	0.44	2/20
SCHEMBL29997546	0.44	2/20
SCHEMBL29752092	0.40	2/20
SCHEMBL22475758	0.35	2/20
SCHEMBL29857355	0.35	2/20
SCHEMBL6014808	1.00	1/20
SCHEMBL29930436	1.00	1/20
Water (SCHEMBL31319504)	0.97	1/20
SCHEMBL1758192	0.50	1/20
SCHEMBL9217699	0.46	1/20
SCHEMBL724972	0.45	1/20
SCHEMBL11374392	0.45	1/20
SCHEMBL21935558	0.45	1/20
Benzoic Acid (SCHEMBL27538220)	0.44	1/20
SCHEMBL8834235	0.44	1/20
SCHEMBL19003399	0.44	1/20

Clinical trials — most relevant to IGFBP1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Insulin-like Growth Factor (IGF-I) in Hemodialysis Patients	PHASE4	COMPLETED
Efficacy of Oral Metformin vs Oral Doxycycline in Treating Acne Vulgaris	PHASE4	COMPLETED
Effects of Oral vs. Non-oral Contraceptives on the GH/IGF-1 Axis	PHASE4	COMPLETED
Metformin Use to Reduce Disparities in Newly Diagnosed Breast Cancer	PHASE4	WITHDRAWN
Effect of Continuous GHRP-3 Infusion at on GH-IGF-I System, Blood Pressure, Glucose, and Insulin Resistance	PHASE1/PHASE2	WITHDRAWN
Study Assessing Potential Predictive Tumor Markers in Metastatic Colorectal Cancer	PHASE2	COMPLETED
Safety Profile of Insulin Like Growth Factor-1 (IGF-I) Administration in Adolescents	PHASE1/PHASE2	COMPLETED
Defined Green Tea Catechins in Treating Patients With Prostate Cancer Undergoing Surgery to Remove the Prostate	PHASE1	COMPLETED
Epidemiology of Insulin Growth Factor (IGF) and Cardiovascular Events	nan	COMPLETED
Atrial Fibrillation in Relationship to Plasma Biomarkers	nan	UNKNOWN
Metabolic and Inflammatory Responses to Hemodialysis and the Effect of a Meal	nan	COMPLETED
Nutrition and Lifestyle Changes in Patients With Previously Untreated Stage I or Stage II Prostate Cancer	nan	COMPLETED
Follow-up to Adult Height of a Cohort of Subjects Born Small for the Gestational Age and Treated With Growth Hormone	nan	COMPLETED
Short-Term Fasting Before Chemotherapy in Treating Patients With Cancer	nan	COMPLETED
Impact of Exercise on Body Composition in Premature Infants	nan	WITHDRAWN
Using IGF-1 for Nutritional Monitoring	nan	COMPLETED
IGF-I Induced Muscle Glucose Uptake and Interstitial IGF-I Concentrations	nan	COMPLETED
To Assess the Level of Adherence of Subjects Receiving SAIZEN® Via Easypod™ in the UK	nan	COMPLETED
Serum IGF-1 and IGF-1Ec in Malignancy Assessment	nan	ACTIVE_NOT_RECRUITING
The Effect of Transcatheter VSD Closure on Children's Appetite, Hormones and Growth	nan	COMPLETED
Effects of Standardized Meals on the Metabolic, Hormonal and Inflammatory Responses in Human	nan	COMPLETED
Role of Biomarkers in Endometrial Cancer Recurrence in Samples From Patients With Stage II, Stage III, or Stage IV Endometrial Cancer	nan	UNKNOWN
Osteoprosis in Type 2 Diabetic Patients- a Cohort Study	nan	UNKNOWN
Assessment of the Diagnostic Role of Serum Insulin-like Growth Factor Binding Protein-3 as a Potential Biomarker for Colorectal Cancer (CRC) in Egypt	nan	NOT_YET_RECRUITING
Lifestyles Of Health And Sustainability for Breast Cancer Survivors	nan	UNKNOWN
Metabolic and Hormonal Effects of 5:2 Intermittent Fasting	nan	COMPLETED
Prognostic Value of Protein IMP3 Expression in Cervical Cancer	nan	COMPLETED
A Low-Insulinemic Dietary Intervention to Reduce Breast Cancer Risk in High-Risk Women	nan	COMPLETED
Adipocytokines in Endometrial Cancer	nan	COMPLETED
DianaWeb: Before and After Study Online Based Participatory Research on Breast Cancer Women	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a IGFBP1 binder may also engage these)

Protein	Name	Similarity
Q5XHC5	—	0.997	Q5XHC5 →
A4IIA2	—	0.994	A4IIA2 →
P21743	—	0.993	P21743 →
P47876	—	0.992	P47876 →
Q6Q484	—	0.991	Q6Q484 →
Q75ZP3	—	0.988	Q75ZP3 →
P24591	—	0.987	P24591 →
P24594	—	0.985	P24594 →
B3F211	—	0.985	B3F211 →
IGFBP5	Insulin-like growth factor-binding protein 5	0.984	landscape →
Q9PTH3	—	0.982	Q9PTH3 →
P47877	—	0.982	P47877 →
Q28985	—	0.982	Q28985 →
P12843	—	0.982	P12843 →
IGFBP3	Insulin-like growth factor-binding protein 3	0.981	landscape →
P16042	—	0.981	P16042 →
P35572	—	0.981	P35572 →
Q90WV8	—	0.981	Q90WV8 →
Q29400	—	0.980	Q29400 →
P47878	—	0.980	P47878 →
P47880	—	0.980	P47880 →
P24853	—	0.980	P24853 →
P49705	—	0.979	P49705 →
Q07079	—	0.979	Q07079 →
P24787	—	0.979	P24787 →
Q91166	—	0.979	Q91166 →
P19336	—	0.979	P19336 →
Q8JGM4	—	0.978	Q8JGM4 →
IGFBP2	Insulin-like growth factor-binding protein 2	0.978	landscape →
O42493	—	0.978	O42493 →