SCHEMBL16003641

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16003615	0.85	TGFBR1 (0.42)	PDE10AKMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL16003310	0.85	PDE10A (0.50)	PDE10AKDM4ECCR1CCR8TGFBR1
	Hydrochloric Acid SCHEMBL28338149	0.83	PDE10A (0.49)	PDE10AKDM4ECCR1CCR8TGFBR1
	SCHEMBL16320446	0.83	TGFBR1 (0.50)	PDE10ACCR1CCR8TGFBR1
	SCHEMBL16003830	0.83	PDE10A (0.47)	PDE10AKDM4ECCR1CCR8TGFBR1
	SCHEMBL16572709	0.83	CYP1A2 (0.38)	PDE10ACYP1A2CYP2C19TGFBR1CNR2
	SCHEMBL16003315	0.82	PDE10A (0.42)	PDE10AMEN1KMT2ACYP1A2CYP2C19
	SCHEMBL16003475	0.82	CNR2 (0.38)	MEN1KMT2ACYP1A2CYP2C19KDM4E
	SCHEMBL16003560	0.82	PDE10A (0.51)	PDE10ACYP1A2CYP2C19KDM4ETGFBR1
	SCHEMBL16352253	0.81	PDE10A (0.46)	PDE10AKDM4ECCR1CCR8TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.