Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 17/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.47 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16003310 | 0.87 | PDE10A (0.50) | TGFBR1PDE10ACCR1CCR8 | |
| Hydrochloric Acid SCHEMBL28338149 | 0.86 | PDE10A (0.49) | TGFBR1PDE10ACCR1CCR8 | |
| SCHEMBL16003830 | 0.86 | PDE10A (0.47) | TGFBR1PDE10ACCR1CCR8 | |
| SCHEMBL16003641 | 0.83 | PDE10A (0.48) | TGFBR1PDE10ACCR1CCR8 | |
| SCHEMBL16352253 | 0.83 | PDE10A (0.46) | TGFBR1PDE10ACCR1CCR8 | |
| SCHEMBL16341782 | 0.81 | PDE10A (0.50) | TGFBR1PDE10A | |
| SCHEMBL16320528 | 0.81 | TGFBR1 (0.43) | TGFBR1PDE10A | |
| SCHEMBL16320863 | 0.79 | TGFBR1 (0.47) | TGFBR1PDE10A | |
| SCHEMBL16323640 | 0.78 | MAPT (0.37) | TGFBR1 | |
| SCHEMBL16561362 | 0.76 | PDE10A (0.47) | TGFBR1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8980889-B2 | Pyrazole derivative | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| US-20140378448-A1 | NOVEL PYRAZOLE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378448-A1 | NOVEL PYRAZOLE DERIVATIVE | PDE10A, PDE3A, PDE5A | TGFBR1 2867/4885PDE10A 1/4885CCR1 4554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.