Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1600514 | 0.85 | IDO1 (0.33) | MEN1KMT2AIDO1SLC6A4SLC6A2 | |
| SCHEMBL1601333 | 0.84 | TACR1 (0.35) | MEN1KMT2ATACR1CFTRFFAR4 | |
| SCHEMBL1600943 | 0.84 | MEN1 (0.40) | MEN1KMT2AIDO1SLC6A4SLC6A2 | |
| SCHEMBL1601502 | 0.82 | TACR1 (0.45) | TACR1 | |
| SCHEMBL1601213 | 0.78 | PDE2A (0.33) | MEN1KMT2AIDO1SLC6A4SLC6A2 | |
| SCHEMBL31435375 | 0.75 | IDO1 (0.35) | IDO1TACR1 | |
| SCHEMBL1600958 | 0.74 | FFAR4 (0.35) | TACR1CFTRFFAR4 | |
| SCHEMBL1600324 | 0.73 | IDO1 (0.41) | IDO1SLC6A4TACR1 | |
| SCHEMBL3954842 | 0.73 | CYP2D6 (0.36) | IDO1TACR1CFTR | |
| SCHEMBL4786749 | 0.73 | SLC6A4 (0.33) | IDO1SLC6A4SLC6A2TACR1CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7919506-B2 | Dibenzyl amine compounds and derivatives | PFIZER INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-7919506-B2 | Dibenzyl amine compounds and derivatives | PFIZER INC. (US) | 2011-04-05 | — | — | US | disclosed |
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | PFIZER INC | 2007-09-13 | — | — | US | disclosed |
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | PFIZER INC | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213371-A1 | Dibenzyl Amine Compounds and Derivatives | APOB, LDLR, CETP | MEN1 1597/4885KMT2A 798/4885IDO1 910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.