⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005042 | 0.85 | GYS1 (0.34) | — | |
| SCHEMBL16005128 | 0.81 | GYS1 (0.36) | — | |
| SCHEMBL16004893 | 0.81 | GYS1 (0.37) | — | |
| SCHEMBL16004961 | 0.75 | ALDH2 (0.33) | — | |
| SCHEMBL19584667 | 0.74 | F2RL1 (0.33) | — | |
| SCHEMBL16005005 | 0.72 | PTPN1 (0.47) | — | |
| SCHEMBL16004830 | 0.71 | GPR35 (0.33) | — | |
| SCHEMBL20870943 | 0.68 | — | — | |
| SCHEMBL23218372 | 0.67 | SIRT2 (0.35) | — | |
| SCHEMBL28911847 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160137633-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES | AJINOMOTO CO., INC. (JP) | 2016-05-19 | — | — | US | disclosed |
| US-9290487-B2 | Pharmaceutical composition for treating diabetes | AJINOMOTO CO., INC. (JP) | 2016-03-22 | — | — | US | disclosed |
| US-20140336376-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES | AJINOMOTO CO., INC. (JP) | 2014-11-13 | — | — | US | disclosed |
| EP-2774917-A1 | PHARMACEUTICAL COMPOSITION FOR TREATING DIABETES | Ajinomoto Co., Inc. (JP) | 2014-09-10 | — | — | EP | disclosed |