Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16005355 | 0.89 | MMP1 (0.46) | CYP1A2MMP1MMP9MMP13CYP2A6 | |
| SCHEMBL1003605 | 0.81 | CTSK (0.49) | CYP1A2CYP2D6SLC6A2CTSKPPARG | |
| SCHEMBL4610682 | 0.79 | CYP1A2 (0.50) | CYP1A2MMP1MMP9MMP13CYP2A6 | |
| SCHEMBL20067118 | 0.79 | CYP1A2 (0.50) | CYP1A2MMP1MMP9MMP13CYP2A6 | |
| SCHEMBL19341333 | 0.77 | CYP2A6 (0.59) | CYP1A2CYP2A6CASRHTR2AHTR2C | |
| SCHEMBL29982408 | 0.76 | CYP1A2 (0.62) | CYP1A2MMP1MMP9MMP13CYP2A6 | |
| SCHEMBL8939501 | 0.76 | CYP1A2 (0.62) | CYP1A2MMP1MMP9MMP13CYP2A6 | |
| SCHEMBL20347157 | 0.76 | SLC13A5 (0.45) | CYP1A2MMP1MMP9MMP13CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL27962083 | 0.76 | CYP2A6 (0.57) | CYP1A2CYP2A6CASRHTR2AHTR2C | |
| SCHEMBL8872531 | 0.75 | CYP1A2 (0.53) | CYP1A2CYP2A6SLC13A5SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | PAH, DDT, NISCH | CYP1A2 15/4885MMP1 4533/4885MMP9 3812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.