Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.45 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859446 | 0.85 | FABP5 (0.46) | FABP5MEN1KMT2APABPC1EIF4H | |
| SCHEMBL2882948 | 0.83 | MEN1 (0.54) | FABP5MEN1KMT2APABPC1EIF4H | |
| SCHEMBL2308927 | 0.81 | FABP5 (0.53) | FABP5MEN1KMT2APABPC1EIF4H | |
| SCHEMBL19475149 | 0.80 | FABP5 (0.49) | FABP5MEN1KMT2APABPC1EIF4H | |
| SCHEMBL28169221 | 0.79 | FABP5 (0.49) | FABP5MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL13609760 | 0.79 | MEN1 (0.50) | FABP5MEN1KMT2APABPC1EIF4H | |
| SCHEMBL18674157 | 0.79 | FABP5 (0.49) | FABP5MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL9399464 | 0.78 | SSTR4 (0.44) | FABP5SMN1; SMN2SLC22A12LMNAMAPT | |
| SCHEMBL7988100 | 0.78 | KDM4E (0.61) | FABP5MEN1KMT2APABPC1EIF4H | |
| SCHEMBL10350646 | 0.77 | LMNA (0.60) | ELANEMEN1KMT2ASMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| EP-2774923-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | UNIV NAGOYA NAT UNIV CORP (JP) | 2016-05-18 | — | — | EP | disclosed |
| US-20160074853-A1 | LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-03-17 | — | — | US | disclosed |
| US-20160074853-A1 | LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2016-03-17 | — | — | US | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-8993777-B2 | Method for producing phenyl-substituted heterocyclic derivative | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2015-03-31 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-09-18 | — | — | US | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
| EP-2774923-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | National University Corporation Nagoya University (JP) | 2014-09-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160074853-A1 | LIGAND, NICKEL COMPLEX COMPRISING THE LIGAND, AND REACTION USING THE NICKEL COMPLEX | NISCH, DDT, TEC | FABP5 2082/4885ELANE 1846/4885MEN1 1615/4885 |
| US-20140275549-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE | PAH, DDT, NISCH | FABP5 3780/4885ELANE 468/4885MEN1 338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.