Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.40 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6631053 | 0.88 | NCF1 (0.47) | FABP5MAPTSMN1; SMN2LMNA | |
| SCHEMBL29380815 | 0.88 | NCF1 (0.47) | FABP5MAPTSMN1; SMN2LMNA | |
| SCHEMBL2308927 | 0.85 | FABP5 (0.53) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2882948 | 0.83 | MEN1 (0.54) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6980607 | 0.83 | FABP5 (0.46) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL6859446 | 0.80 | FABP5 (0.46) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL28624547 | 0.80 | FABP5 (0.46) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL13609760 | 0.80 | MEN1 (0.50) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL16005654 | 0.80 | FABP5 (0.49) | FABP5MEN1KMT2AKDM4EMAPT | |
| SCHEMBL18674157 | 0.80 | FABP5 (0.49) | FABP5MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184589-A1 | A VERSATILE LIGAND FOR PALLADIUM-CATALYZED META-C-H FUNCTIONALIZATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2017-10-26 | — | — | WO | disclosed |