Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8645031 | 0.86 | KDM4E (0.43) | MLYCDEPHX2GAATDP1MAOA | |
| SCHEMBL1119918 | 0.85 | RECQL (0.37) | RECQLMLYCDEPHX2GAATDP1 | |
| SCHEMBL15146916 | 0.80 | TSHR (0.46) | RECQLEPHX2GAAKDM4EHIF1A | |
| SCHEMBL7660758 | 0.80 | PTPRC (0.40) | RECQLGAATDP1MAOAMAOB | |
| SCHEMBL1709282 | 0.79 | MEN1 (0.48) | RECQLMLYCDEPHX2GAATDP1 | |
| SCHEMBL4810916 | 0.79 | MLYCD (0.40) | RECQLMLYCDEPHX2GAATDP1 | |
| SCHEMBL4810925 | 0.79 | TDP1 (0.41) | RECQLMLYCDEPHX2GAATDP1 | |
| SCHEMBL23631428 | 0.77 | MLYCD (0.39) | RECQLMLYCDEPHX2GAATDP1 | |
| SCHEMBL947583 | 0.77 | CASP2 (0.48) | RECQLMLYCDEPHX2GAAHPGD | |
| SCHEMBL16761792 | 0.77 | ECE1 (0.41) | RECQLMLYCDEPHX2GAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014134457-A2 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN, INC. (US) | 2014-09-04 | — | — | WO | disclosed |