SCHEMBL16007129

SCHEMBL16007129

O=C(O)CCC(=O)OCCOCCOCCOC(=O)CCC(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
EGLN1 Q9GZT9 3/20 0.45
ALKBH5 Q6P6C2 1/20 0.45
SUCNR1 Q9BXA5 1/20 0.45
ADRA2A P08913 1/20 0.44
ADRA1A P35348 1/20 0.44
TDP1 Q9NUW8 1/20 0.43
BLM P54132 2/20 0.43
MAPT P10636 1/20 0.43
KDM6B O15054 1/20 0.43
KDM5C P41229 1/20 0.43
PHF8 Q9UPP1 1/20 0.43
KDM2A Q9Y2K7 1/20 0.43
DGKA P23743 1/20 0.41
NPC1 O15118 1/20 0.40
TSHR P16473 5/20 0.39
ALDH1A1 P00352 4/20 0.39
TP53 P04637 2/20 0.39
HIF1A Q16665 2/20 0.39
HSD17B10 Q99714 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14153186 1.00 LMNA (0.45) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL127836 1.00 LMNA (0.45) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL16996654 1.00 LMNA (0.45) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL15445484 0.93 DGKA (0.52) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL409092 0.92 LMNA (0.53) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL21876953 0.91 MEN1 (0.46) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL7715014 0.91 MEN1 (0.46) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL13821164 0.91 NPC1 (0.46) LMNAEGLN1ALKBH5SUCNR1ADRA2A
SCHEMBL421182 0.91 DGKA (0.50) LMNAADRA2AADRA1ATDP1DGKA
SCHEMBL1986730 0.91 MEN1 (0.46) LMNAEGLN1ALKBH5SUCNR1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170037280-A1 ANTISTATIC ADHESIVE COMPOSITION AND POLARIZING PLATE MANUFACTURED USING SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2017-02-09 US disclosed
US-20170037280-A1 ANTISTATIC ADHESIVE COMPOSITION AND POLARIZING PLATE MANUFACTURED USING SAME DONGWOO FINE-CHEM CO., LTD. (KR) 2017-02-09 US disclosed
US-20140256696-A1 Steroid conjugates ALLERGAN, INC. (US) 2014-09-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256696-A1 Steroid conjugates CYP21A2, CYP17A1, HSD17B2 LMNA 3852/4885EGLN1 4322/4885ALKBH5 2901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.