SCHEMBL16010716

SCHEMBL16010716

O=C(O)CCCCCCCCCCN1CCN(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 1/20 0.54
▸ KMT2A Q03164 1/20 0.54
▸ NPSR1 Q6W5P4 1/20 0.54
▸ CA1 P00915 3/20 0.53
▸ CA2 P00918 3/20 0.53
▸ CA7 P43166 3/20 0.53
▸ CA9 Q16790 2/20 0.53
▸ SMN1; SMN2 Q16637 2/20 0.53
▸ NPC1 O15118 1/20 0.53
▸ RAB9A P51151 1/20 0.53
▸ CYP2C19 P33261 2/20 0.51
▸ HTR2A P28223 2/20 0.50
▸ OPRM1 P35372 2/20 0.50
▸ HTR1A P08908 2/20 0.50
▸ HRH1 P35367 2/20 0.50
▸ TEAD3 Q99594 1/20 0.50
▸ ENPP2 Q13822 1/20 0.50
▸ DRD4 P21917 1/20 0.50
▸ TNKS O95271 1/20 0.49
▸ PARP1 P09874 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29234163 0.99 MEN1 (0.56) MEN1KMT2ANPSR1CA1CA2
SCHEMBL9633964 0.95 MEN1 (0.57) MEN1KMT2ANPSR1CA1CA2
SCHEMBL27610472 0.87 NPSR1 (0.54) MEN1KMT2ANPSR1CA1CA2
SCHEMBL22788750 0.87 MEN1 (0.57) MEN1KMT2ANPSR1CA1CA2
SCHEMBL29234309 0.86 HTT (0.55) MEN1KMT2ANPSR1CA1CA2
SCHEMBL21527984 0.86 MEN1 (0.53) MEN1KMT2ANPSR1CA1CA2
SCHEMBL5542172 0.86 NPSR1 (0.56) MEN1KMT2ANPSR1CA1CA2
SCHEMBL27629467 0.86 SIGMAR1 (0.56) MEN1KMT2ANPSR1CA1CA2
SCHEMBL5154279 0.85 MEN1 (0.58) MEN1KMT2ANPSR1CA1CA2
SCHEMBL5541709 0.85 MEN1 (0.52) MEN1KMT2ANPSR1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2023-08-01 — — US disclosed
EP-3939972-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2022-01-19 — — EP disclosed
US-20210338850-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2021-11-04 — — US disclosed
EP-3545978-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2021-09-08 — — EP disclosed
US-10898598-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2021-01-26 — — US disclosed
EP-3545978-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS Molecular Insight Pharmaceuticals, Inc. (US) 2019-10-02 — — EP disclosed
EP-3300746-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2019-05-15 — — EP disclosed
US-20190134237-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2019-05-09 — — US disclosed
US-10201624-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2019-02-12 — — US disclosed
US-10086096-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2018-10-02 — — US disclosed
US-20170296683-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2017-10-19 — — US disclosed
EP-2943227-B1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARM INC (US) 2017-09-20 — — EP disclosed
US-20160346410-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2016-12-01 — — US disclosed
US-9447121-B2 Triazine based radiopharmaceuticals and radioimaging agents MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2016-09-20 — — US disclosed
US-20140255306-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2014-09-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210338850-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA2, PSMA5, PSMA1 MEN1 104/4885KMT2A 1018/4885NPSR1 421/4885
US-10898598-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 MEN1 104/4885KMT2A 1018/4885NPSR1 421/4885
US-11712485-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 MEN1 104/4885KMT2A 1018/4885NPSR1 421/4885
US-20170296683-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA2, PSMA5, PSMA1 MEN1 104/4885KMT2A 1018/4885NPSR1 421/4885
US-20160346410-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA5, PSMA2, PSMA1 MEN1 141/4885KMT2A 1288/4885NPSR1 679/4885
US-20140255306-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA5, PSMA2, PSMA1 MEN1 141/4885KMT2A 1288/4885NPSR1 679/4885
US-10086096-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA2, PSMA5, PSMA1 MEN1 104/4885KMT2A 1018/4885NPSR1 421/4885
US-10201624-B2 Triazine based radiopharmaceuticals and radioimaging agents PSMA5, PSMA2, PSMA1 MEN1 141/4885KMT2A 1288/4885NPSR1 679/4885
US-20190134237-A1 TRIAZINE BASED RADIOPHARMACEUTICALS AND RADIOIMAGING AGENTS PSMA2, PSMA5, PSMA1 MEN1 104/4885KMT2A 1018/4885NPSR1 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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