Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | TEAD3 | Q99594 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5542172 | 0.99 | NPSR1 (0.56) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5536999 | 0.95 | MEN1 (0.57) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5151317 | 0.89 | MEN1 (0.59) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5545410 | 0.88 | HRH1 (0.54) | NPSR1MEN1KMT2ACA1CA2 | |
| SCHEMBL16010716 | 0.87 | MEN1 (0.54) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL22788750 | 0.87 | MEN1 (0.57) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL5541594 | 0.86 | HRH1 (0.55) | NPSR1MEN1KMT2ACA1CA2 | |
| SCHEMBL5540188 | 0.86 | HRH2 (0.52) | KMT2ACA1CA2CA7CYP2C19 | |
| SCHEMBL27629467 | 0.86 | SIGMAR1 (0.56) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL29234163 | 0.86 | MEN1 (0.56) | NPSR1MEN1KMT2ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |