Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 10/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.44 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17153933 | 0.81 | EGFR (0.57) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL31203371 | 0.79 | CA1 (0.64) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL16010939 | 0.79 | HDAC4 (0.62) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL16023753 | 0.77 | HDAC4 (0.64) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL17154003 | 0.77 | HDAC4 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL18522430 | 0.76 | NAMPT (0.50) | — | |
| SCHEMBL17153936 | 0.75 | AAK1 (0.58) | HDAC3HDAC1HDAC2HDAC8HDAC10 | |
| SCHEMBL27200474 | 0.75 | TERT (0.44) | CYP3A4 | |
| SCHEMBL1400198 | 0.75 | GAA (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29895464 | 0.75 | GAA (0.55) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994122-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C Biopharma, LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| WO-2014138508-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA, LLC (US) | 2014-09-12 | — | — | WO | disclosed |
| WO-2014138508-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA, LLC (US) | 2014-09-12 | — | — | WO | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | RELA, CBFB, CREBBP | HDAC3 206/4885HDAC1 180/4885HDAC2 228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.