Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 15/20 | 0.66 |
| ▸ | MEF2D | Q14814 | 6/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1063952 | 0.82 | HDAC1 (0.58) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL1060811 | 0.81 | HDAC1 (0.60) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL16010937 | 0.80 | HDAC4 (0.45) | HDAC4MEF2DHDAC1HDAC3HDAC2 | |
| SCHEMBL16011052 | 0.79 | HDAC4 (0.60) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL16010981 | 0.79 | HDAC4 (1.00) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL16011100 | 0.79 | HDAC4 (0.63) | HDAC4MEF2DHDAC1HDAC3HDAC2 | |
| SCHEMBL1065607 | 0.78 | HDAC1 (0.61) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL16010906 | 0.78 | HDAC3 (0.52) | HDAC4HDAC1HDAC3HDAC2HDAC10 | |
| SCHEMBL1064516 | 0.75 | HDAC4 (0.62) | HDAC4MEF2DHDAC1HDAC3HDAC2 | |
| SCHEMBL1063215 | 0.74 | HDAC3 (0.55) | HDAC4MEF2DHDAC1HDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2994122-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C Biopharma, LLC (US) | 2016-03-16 | — | — | EP | disclosed |
| US-9133105-B2 | Transcription factor modulators | C&C BIOPHARMA, LLC (US) | 2015-09-15 | — | — | US | disclosed |
| WO-2014138508-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA, LLC (US) | 2014-09-12 | — | — | WO | disclosed |
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | C & C BIOPHARMA LLC (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256775-A1 | NOVEL TRANSCRIPTION FACTOR MODULATORS | RELA, CBFB, CREBBP | HDAC4 224/4885MEF2D 255/4885HDAC1 180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.