Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.41 |
| ▸ | ACP1 | P24666 | 3/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17351910 | 1.00 | PTPN1 (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL16012351 | 1.00 | PTPN1 (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17351911 | 1.00 | PTPN1 (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17356811 | 0.74 | PTPN1 (0.53) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17356818 | 0.74 | PTPN1 (0.53) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL17356821 | 0.74 | PTPN1 (0.53) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL10783860 | 0.66 | PLA2G2A (0.41) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL27946139 | 0.62 | HSD17B3 (0.53) | PTPN1ACP1CDC25BMAPTRECQL | |
| SCHEMBL23397936 | 0.59 | KMT2A (0.80) | PTPN1MAPTTDP1 | |
| SCHEMBL23530132 | 0.59 | KMT2A (0.80) | PTPN1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2965758-B1 | OSTEOPONTIN PRODUCTION INHIBITOR COMPRISING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | UNIV TOHOKU (JP) | 2018-01-03 | — | — | EP | disclosed |
| CN-105209038-B | Osteopontin with dictyostelium discoideum pyrone derivative or dihydro dictyostelium discoideum pyrone derivative as active ingredient produces inhibitor | 国立大学法人东北大学 | 2017-06-09 | — | — | CN | disclosed |
| US-9463188-B2 | Osteopontin production inhibitor containing dictyopyrone derivative or dihydrodictyopyrone derivative as active ingredient | TOHOKU UNIVERSITY (JP) | 2016-10-11 | — | — | US | disclosed |
| EP-2965758-A1 | OSTEOPONTIN PRODUCTION INHIBITOR COMPRISING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | Tohoku University (JP) | 2016-01-13 | — | — | EP | disclosed |
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | TOHOKU UNIVERSITY (JP) | 2015-12-24 | — | — | US | disclosed |
| WO-2014136161-A1 | OSTEOPONTIN PRODUCTION INHIBITOR COMPRISING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | 国立大学法人東北大学 (JP) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150366851-A1 | OSTEOPONTIN PRODUCTION INHIBITOR CONTAINING DICTYOPYRONE DERIVATIVE OR DIHYDRODICTYOPYRONE DERIVATIVE AS ACTIVE INGREDIENT | SPPL2B, DPYSL3, DIAPH1 | PTPN1 1624/4885ACP1 142/4885CDC25B 382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.