Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.74 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.74 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.74 |
| ▸ | PPARG | P37231 | 7/20 | 0.74 |
| ▸ | PPARD | Q03181 | 7/20 | 0.74 |
| ▸ | PPARA | Q07869 | 7/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.74 |
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.74 |
| ▸ | TLR2 | O60603 | 2/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.74 |
| ▸ | FABP4 | P15090 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.74 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | ESR1 | P03372 | 1/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | PDE4A | P27815 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492074 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| Adipic Acid SCHEMBL11453017 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL775625 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL227364 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL20943305 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL25195763 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL18558704 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL16829864 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL8421567 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD | |
| SCHEMBL10780484 | 1.00 | FFAR4 (0.74) | FFAR4FFAR1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317944-A | Acyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-118234707-A | Cyclic lipids and methods of use thereof | 雷纳嘉德医疗管理公司 | 2024-06-21 | — | — | CN | disclosed |
| US-20220402862-A1 | IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES | INTELLIA THERAPEUTICS, INC. | 2022-12-22 | — | — | US | disclosed |
| US-20220402862-A1 | IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES | INTELLIA THERAPEUTICS, INC. | 2022-12-22 | — | — | US | disclosed |
| US-11420933-B2 | Lipids and lipid compositions for the delivery of active agents | NOVARTIS AG (CH) | 2022-08-23 | — | — | US | disclosed |
| EP-3959191-A1 | IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES | Intellia Therapeutics, Inc. (US) | 2022-03-02 | — | — | EP | disclosed |
| CN-114127044-A | Ionizable amine lipids and lipid nanoparticles | 英特利亚治疗股份有限公司 | 2022-03-01 | — | — | CN | disclosed |
| EP-3623361-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-08-18 | — | — | EP | disclosed |
| EP-3608308-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| EP-3608308-B1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2021-07-21 | — | — | EP | disclosed |
| US-20160311759-A1 | Lipids and Lipid Compositions for the Delivery of Active Agents | NOVARTIS AG (CH) | 2016-10-27 | — | — | US | disclosed |
| EP-3083556-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | Novartis AG (CH) | 2016-10-26 | — | — | EP | disclosed |
| US-20160106842-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2016-04-21 | — | — | US | disclosed |
| US-20160106842-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2016-04-21 | — | — | US | disclosed |
| US-20160106842-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. | 2016-04-21 | — | — | US | disclosed |
| WO-2016010840-A1 | METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST | NOVARTIS AG (CH) | 2016-01-21 | — | — | WO | disclosed |
| EP-2964608-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | Novartis AG (CH) | 2016-01-13 | — | — | EP | disclosed |
| WO-2015095340-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2015-06-25 | — | — | WO | disclosed |
| WO-2015095340-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2015-06-25 | — | — | WO | disclosed |
| WO-2014136086-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | NOVARTIS AG (CH) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11420933-B2 | Lipids and lipid compositions for the delivery of active agents | LPAR1, LPAR4, LIPA | FFAR4 208/4885FFAR1 189/4885GPR84 956/4885 |
| US-20220402862-A1 | IONIZABLE AMINE LIPIDS AND LIPID NANOPARTICLES | PHOSPHO1, SGMS1, SGMS2 | FFAR4 695/4885FFAR1 1223/4885GPR84 1499/4885 |
| US-20160106842-A1 | LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS | LIPA, LPAR1, LPAR4 | FFAR4 188/4885FFAR1 193/4885GPR84 648/4885 |
| US-20160311759-A1 | Lipids and Lipid Compositions for the Delivery of Active Agents | PHOSPHO1, SGMS1, ABCB4 | FFAR4 165/4885FFAR1 174/4885GPR84 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.