SCHEMBL16014111

SCHEMBL16014111

CN(C)c1ccc(C2(c3ccc(N(C)C)cc3)C(=O)c3ccccc3C2=O)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.47
MEN1 O00255 5/20 0.47
KMT2A Q03164 5/20 0.47
MAPT P10636 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
HPGD P15428 4/20 0.46
MAPK1 P28482 4/20 0.46
RAB9A P51151 4/20 0.46
APP P05067 3/20 0.46
SNCA P37840 3/20 0.46
TSHR P16473 3/20 0.46
PDGFRB P09619 2/20 0.46
CYP3A4 P08684 2/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
NPC1 O15118 2/20 0.46
GMNN O75496 1/20 0.46
MTOR P42345 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7967132 0.77 MAPT (0.54) ALDH1A1MEN1KMT2AMAPTMAPK1
SCHEMBL19754368 0.72 ALDH1A1 (0.46) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL9575837 0.71 RECQL (0.60) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL14596393 0.71 KMT2A (0.44) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL50863 0.70 TDP1 (0.75) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL29139759 0.69 ALDH1A1 (0.52) ALDH1A1MEN1KMT2AMAPTTDP1
Phthalimide SCHEMBL28091497 0.68 GSK3B (0.62) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL19698857 0.68 ALDH1A1 (0.58) ALDH1A1MEN1KMT2AMAPTTDP1
SCHEMBL65261 0.65 ALDH1A1 (1.00) ALDH1A1MEN1KMT2AMAPTTDP1
Sulfur Dioxide SCHEMBL22235470 0.65 ALDH1A1 (0.53) ALDH1A1MEN1KMT2AMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160040061-A1 FLEXIBLE POLYMERIC MATERIALS CONTAINING TRIBOLUMINESCENT COMPOUNDS, PROTECTIVE DEVICES CONTAINING SUCH MATERIALS, AND METHODS OF MANUFACTURING THE SAME FULLPROOF LLC (US) 2016-02-11 US disclosed
EP-2964723-A2 FLEXIBLE POLYMERIC MATERIALS CONTAINING TRIBOLUMINESCENT COMPOUNDS, PROTECTIVE DEVICES CONTAINING SUCH MATERIALS, AND METHODS OF MANUFACTURING THE SAME Fullproof, LLC (US) 2016-01-13 EP disclosed
WO-2014138534-A2 FLEXIBLE POLYMERIC MATERIALS CONTAINING TRIBOLUMINESCENT COMPOUNDS, PROTECTIVE DEVICES CONTAINING SUCH MATERIALS, AND METHODS OF MANUFACTURING THE SAME FULLPROOF, LLC (US) 2014-09-12 WO disclosed