SCHEMBL160150

SCHEMBL160150

Cc1cccc(-c2cccc(C)c2)c1.N=C=O.N=C=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.50
PTPN5 P54829 1/20 0.44
CHRNB4 P30926 1/20 0.44
CHRNA3 P32297 1/20 0.44
RAB9A P51151 3/20 0.44
DHODH Q02127 1/20 0.43
AR P10275 1/20 0.43
FYN P06241 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
DYRK1B Q9Y463 1/20 0.43
NPC1 O15118 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
PGR P06401 1/20 0.42
AKR1C2 P52895 1/20 0.42
AKR1C1 Q04828 1/20 0.42
HSD17B1 P14061 1/20 0.42
HSD17B2 P37059 1/20 0.42
ALDH1A1 P00352 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28745195 1.00 ACHE (0.50) ACHEPTPN5CHRNB4CHRNA3RAB9A
SCHEMBL8062082 1.00 ACHE (0.50) ACHEPTPN5CHRNB4CHRNA3RAB9A
SCHEMBL29401977 1.00 ACHE (0.50) ACHEPTPN5CHRNB4CHRNA3RAB9A
Methane SCHEMBL29103903 0.98 ACHE (0.48) ACHEPTPN5CHRNB4CHRNA3RAB9A
SCHEMBL8847177 0.94 NPC1 (0.47) ACHEPTPN5RAB9ADHODHNPC1
SCHEMBL30636070 0.92 HSD17B1 (0.45) ACHEPTPN5DHODHARFYN
SCHEMBL29136532 0.92 HSD17B1 (0.45) ACHEPTPN5DHODHARFYN
SCHEMBL28526052 0.88 AR (0.41) ACHEPTPN5CHRNB4CHRNA3RAB9A
M-Xylene SCHEMBL31383510 0.87 ACHE (0.67) ACHENPC1TSHRALDH1A1MAPT
M-Xylene SCHEMBL27020 0.87 ACHE (0.67) ACHENPC1TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3602 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720199-A1 SELF-CROSSLINKABLE URETHANE (METH)ACRYLATES ARKEMA France (FR) 2026-04-08 EP claimed
US-20260028444-A1 RECYCLING POLYOLS PRODUCED FROM SEAT COVER MATERIALS FAURECIA SIEGES DAUTOMOBILE (FR) 2026-01-29 US claimed
US-20250368823-A1 MODIFIED POLYURETHANE MATERIAL WITH EXCELLENT RAIN EROSION RESISTANCE AND WEATHER RESISTANCE, AND PREPARATION METHOD AND USE THEREOF ZHUZHOU TIMES NEW MATERIALTECHNOLOGYCO.,LTD, (CN) 2025-12-04 US claimed
EP-4653482-A1 MODIFIED POLYURETHANE MATERIAL HAVING EXCELLENT RAIN EROSION RESISTANCE AND WEATHER RESISTANCE, PREPARATION METHOD THEREFOR, AND USE THEREOF Zhuzhou Times New Material Technology Co., Ltd. (CN) 2025-11-26 EP claimed
US-20250320345-A1 RECYCLING POLYOLS PRODUCED FROM MOLDED POLYURETHANE FOAM FAURECIA SIEGES DAUTOMOBILE (FR) 2025-10-16 US claimed
EP-3953407-B1 2-COMPONENT POLYURETHANE COATINGS WITH IMPROVED POT LIFE WITHOUT LOST WEATHERING STABILITY COVESTRO DEUTSCHLAND AG (DE) 2025-04-30 EP claimed
EP-3538578-B1 EXPANDED THERMOPLASTIC POLYURETHANE PARTICLES, METHOD FOR THEIR MANUFACTURE AND METHOD FOR PRODUCING A MOULDED PART BASF SE (DE) 2025-03-05 EP claimed
US-12241001-B2 Systems for priming and adhesion of flooring COVESTRO DEUTSCHLAND AG (DE) 2025-03-04 US claimed
US-12215183-B2 Expanded thermoplastic polyurethane beads, production thereof and production of a molded part BASF SE (DE) 2025-02-04 US claimed
US-20240409679-A1 METHOD FOR PRODUCING A MIXTURE OF ALKOXYLATED POLYPHENOLS AND USE OF SAID MIXTURE SOPREMA (FR) 2024-12-12 US claimed
US-5574092-A MELT PROCESSABILITY THE DOW CHEMICAL COMPANY (US) 1996-11-12 US claimed
US-5545708-A POLYETHERURETHANE COPOLYMERS; CATHETERS BECTON, DICKINSON AND COMPANY (US) 1996-08-13 US claimed
US-5530989-A Dual durometer handles THE DOW CHEMICAL COMPANY (US) 1996-07-02 US claimed
WO-1996019325-A1 DUAL DUROMETER HANDLES THE DOW CHEMICAL COMPANY (US) 1996-06-27 WO claimed
US-5344484-A Decorative door skin MASONITE CORPORATION (US) 1994-09-06 US claimed
US-5334673-A From a thermosetting composition cured with a slow-reacting polyamine ACUSHNET CO. (US) 1994-08-02 US claimed
US-5159050-A Protonation; complexed with anticoagulant BECTON, DICKINSON AND COMPANY (US) 1992-10-27 US claimed
US-5159051-A Tertiary amines in polymer chain; complexes; antithrombogenic agents BECTON, DICKINSON AND COMPANY (US) 1992-10-27 US claimed
US-5114793-A Crosslinked binder with magnetic and nonmagnetic layers KAO CORPORATION (JP) 1992-05-19 US claimed
US-4849262-A Pigment printing pastes and dyeing liquors containing stable dispersions of finely divided solid polyisocyanates BASF AKTIENGESELLSCHAFT (DE) 1989-07-18 US claimed