Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 6/20 | 0.35 |
| ▸ | GSK3B | P49841 | 5/20 | 0.35 |
| ▸ | DPP4 | P27487 | 5/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649307 | 1.00 | GSK3A (0.35) | GSK3AGSK3BDPP4DPP8DPP7 | |
| SCHEMBL16649516 | 0.74 | — | — | |
| SCHEMBL1606552 | 0.69 | DPP4 (0.34) | GSK3AGSK3BDPP4DPP8DPP7 | |
| SCHEMBL5017231 | 0.68 | HSD11B1 (0.47) | GSK3AGSK3BDPP4DPP8DPP7 | |
| SCHEMBL1605453 | 0.66 | CNR2 (0.37) | GSK3AGSK3BDPP4DPP8DPP7 | |
| SCHEMBL12313398 | 0.62 | PKM (0.40) | DPP4DPP8HSD11B1EPHX2 | |
| SCHEMBL13444794 | 0.62 | GRIN2D (0.56) | DPP4DPP8EPHX2 | |
| SCHEMBL5614585 | 0.62 | GRIN2D (0.56) | DPP4DPP8EPHX2 | |
| SCHEMBL15114218 | 0.61 | GRIN2D (0.47) | DPP4DPP8HSD11B1CNR1CNR2 | |
| SCHEMBL2853219 | 0.61 | DPP4 (0.50) | DPP4DPP8DPP7EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828994-B2 | Di- and tri-substituted oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof | SANOFI (FR) | 2014-09-09 | — | — | US | disclosed |