Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | PPIA | P62937 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1919991 | 0.92 | LMNA (0.72) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL28448203 | 0.88 | HPGD (0.71) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL2338199 | 0.88 | HPGD (0.76) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL1918679 | 0.87 | LMNA (0.52) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL28011313 | 0.87 | MAPT (0.54) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL16447278 | 0.87 | HPGD (0.65) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL15476491 | 0.87 | HPGD (0.65) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL16015335 | 0.86 | LMNA (0.61) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL15369546 | 0.86 | LMNA (0.68) | LMNAHPGDMAPTL3MBTL1RAB9A | |
| SCHEMBL5838451 | 0.86 | MEN1 (0.63) | HPGDMAPTL3MBTL1RAB9ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037641-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2024-07-16 | — | — | US | disclosed |
| US-11466319-B2 | Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-10-11 | — | — | US | disclosed |
| US-11359235-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2022-06-14 | — | — | US | disclosed |
| US-20210147928-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-10787573-B2 | Multimeric protected fluorescent reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-10676788-B2 | Modified nucleotide reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-06-09 | — | — | US | disclosed |
| US-10669299-B2 | Protected dye-labeled reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-06-02 | — | — | US | disclosed |
| US-20170321268-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-11-09 | — | — | US | disclosed |
| US-20170321268-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-11-09 | — | — | US | disclosed |
| US-20170145502-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20170145502-A1 | MODIFIED NUCLEOTIDE REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2017-05-25 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-9201001-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2015-12-01 | — | — | US | disclosed |
| US-9201001-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2015-12-01 | — | — | US | disclosed |
| US-20140357894-A1 | VISUAL DETECTION OF FLUORIDE IONS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2014-12-04 | — | — | US | disclosed |
| US-20140357894-A1 | VISUAL DETECTION OF FLUORIDE IONS | EMPIRE TECHNOLOGY DEVELOPMENT LLC | 2014-12-04 | — | — | US | disclosed |
| US-8828735-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2014-09-09 | — | — | US | disclosed |
| US-8828735-B2 | Visual detection of fluoride ions | INDIAN INSTITUTE OF TECHNOLOGY MADRAS (IN) | 2014-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11359235-B2 | Modified nucleotide reagents | POLL, POLN, POLM | LMNA 375/4885HPGD 1398/4885MAPT 3684/4885 |
| US-20170321268-A1 | MODIFIED NUCLEOTIDE REAGENTS | POLL, POLN, POLM | LMNA 375/4885HPGD 1398/4885MAPT 3684/4885 |
| US-10669299-B2 | Protected dye-labeled reagents | POLL, POLB, POLM | LMNA 265/4885HPGD 1167/4885MAPT 3847/4885 |
| US-12037641-B2 | Modified nucleotide reagents | POLL, POLN, POLM | LMNA 375/4885HPGD 1398/4885MAPT 3684/4885 |
| US-20140357894-A1 | VISUAL DETECTION OF FLUORIDE IONS | HNRNPL, HNRNPLL, ARAF | LMNA 1059/4885HPGD 2867/4885MAPT 1641/4885 |
| US-20210147928-A1 | LABELED NUCLEOTIDE ANALOGS, REACTION MIXTURES, AND METHODS AND SYSTEMS FOR SEQUENCING | POLL, POLN, POLB | LMNA 438/4885HPGD 987/4885MAPT 4031/4885 |
| US-11466319-B2 | Labeled nucleotide analogs, reaction mixtures, and methods and systems for sequencing | POLL, POLN, POLB | LMNA 438/4885HPGD 987/4885MAPT 4031/4885 |
| US-10676788-B2 | Modified nucleotide reagents | POLL, POLN, POLM | LMNA 375/4885HPGD 1398/4885MAPT 3684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.