Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | RXRA | P19793 | 3/20 | 0.60 |
| ▸ | RXRB | P28702 | 2/20 | 0.60 |
| ▸ | RXRG | P48443 | 1/20 | 0.60 |
| ▸ | MRGPRX4 | Q96LA9 | 6/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12563268 | 0.92 | RXRA (0.60) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL1936315 | 0.90 | MRGPRX4 (0.64) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL1936167 | 0.90 | MRGPRX4 (0.57) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL16015342 | 0.86 | LMNA (0.67) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL793724 | 0.85 | MEN1 (0.65) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL15369572 | 0.84 | RXRA (0.58) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL28011313 | 0.84 | MAPT (0.54) | MEN1KMT2AMAPTMAPK1TDP1 | |
| SCHEMBL69666 | 0.84 | RXRA (0.70) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL11762649 | 0.84 | RXRA (0.61) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL642448 | 0.83 | MEN1 (0.63) | MEN1KMT2ARXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2721000-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | The Royal Institution for the Advancement of Learning / McGill University (CA) | 2014-04-23 | — | — | EP | disclosed |
| WO-2012171114-A1 | SYNTHETIC EPIGALLOCATECHIN GALLATE (EGCG) ANALOGS | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2012-12-20 | — | — | WO | disclosed |
| US-7122573-B2 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL (US) | 2006-10-17 | — | — | US | disclosed |
| US-7109236-B2 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL (US) | 2006-09-19 | — | — | US | disclosed |
| EP-1581512-A2 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | SRI INTERNATIONAL (US) | 2005-10-05 | — | — | EP | disclosed |
| US-20040192723-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL | 2004-09-30 | — | — | US | disclosed |
| WO-2004052873-A9 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | STANFORD RES INST INT (US) | 2004-08-12 | — | — | WO | disclosed |
| WO-2004052873-A2 | ANALOGS OF GREEN TEA POLYPHENOLS AS CHEMOTHERAPEUTIC AND CHEMOPREVENTIVE AGENTS | SRI INTERNATIONAL (US) | 2004-06-24 | — | — | WO | disclosed |
| US-20040110790-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | SRI INTERNATIONAL | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192723-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | TEAD4, TEAD3, TEAD1 | MEN1 3729/4885KMT2A 2705/4885MAPT 2442/4885 |
| US-20040110790-A1 | Analogs of green tea polyphenols as chemotherapeutic and chemopreventive agents | TEAD4, TEAD3, TEAD1 | MEN1 3729/4885KMT2A 2705/4885MAPT 2442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.