Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | KDM5C | P41229 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.44 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23585019 | 0.74 | LMNA (0.56) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL14261186 | 0.68 | — | — | |
| SCHEMBL6562134 | 0.65 | LMNA (1.00) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL6536861 | 0.64 | LMNA (0.56) | LMNAPOLBTSHR | |
| SCHEMBL26211582 | 0.63 | PHF8 (1.00) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL6124941 | 0.62 | KDM4E (0.64) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL25654026 | 0.62 | — | — | |
| SCHEMBL6537134 | 0.61 | LMNA (0.52) | LMNAKDM4ETSHR | |
| SCHEMBL20374795 | 0.60 | PHF8 (0.68) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL16204454 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828433-B2 | Hydrogel bioscaffoldings and biomedical device coatings | ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) | 2014-09-09 | — | — | US | disclosed |