Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | KDM5C | P41229 | 1/20 | 0.54 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.54 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.54 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL836383 | 0.83 | LMNA (0.82) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL10051078 | 0.77 | LMNA (0.52) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL14261186 | 0.76 | — | — | |
| SCHEMBL16015568 | 0.74 | LMNA (0.46) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL19368291 | 0.73 | LMNA (0.48) | LMNATSHRCA1CA2CA9 | |
| SCHEMBL10044121 | 0.72 | — | — | |
| SCHEMBL9257453 | 0.72 | — | — | |
| SCHEMBL6562134 | 0.72 | LMNA (1.00) | LMNAKDM4EKDM5CEGLN1PHF8 | |
| SCHEMBL13385714 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL23529597 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3842459-A1 | ANTI-CD123 ANTIBODIES AND CONJUGATES AND DERIVATIVES THEREOF | ImmunoGen, Inc. (US) | 2021-06-30 | — | — | EP | disclosed |