Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 8/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258622 | 1.00 | BTN3A1 (0.49) | BTN3A1ELANEHPGDALDH1A1MEN1 | |
| SCHEMBL16258628 | 0.95 | BTN3A1 (0.45) | BTN3A1ELANEHPGDALDH1A1MEN1 | |
| SCHEMBL15343937 | 0.95 | MEN1 (0.46) | BTN3A1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL15343939 | 0.95 | MEN1 (0.46) | BTN3A1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL16575733 | 0.90 | BTN3A1 (0.44) | BTN3A1ELANEHPGDALDH1A1TSHR | |
| SCHEMBL16258631 | 0.89 | MEN1 (0.42) | BTN3A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16258629 | 0.89 | MEN1 (0.42) | BTN3A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30583779 | 0.89 | MEN1 (0.42) | BTN3A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22065039 | 0.89 | BTN3A1 (0.51) | BTN3A1ELANEALDH1A1 | |
| SCHEMBL28986476 | 0.87 | BTN3A1 (0.41) | BTN3A1ELANEHPGDALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805960-A1 | Methods for the preparation of diasteromerically pure phosphoramidate prodrugs | GILEAD SCIENCES, INC. (US) | 2014-11-26 | — | — | EP | disclosed |
| EP-2596004-B1 | METHODS FOR THE PREPARATION OF DIASTEROMERICALLY PURE PHOSPHORAMIDATE PRODRUGS | GILEAD SCIENCES INC (US) | 2014-09-10 | — | — | EP | disclosed |