Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 6/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16258622 | 0.95 | BTN3A1 (0.49) | BTN3A1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL16015977 | 0.95 | BTN3A1 (0.49) | BTN3A1HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL15343937 | 0.94 | MEN1 (0.46) | BTN3A1CARM1PRMT6HPGDALDH1A1 | |
| SCHEMBL15343939 | 0.94 | MEN1 (0.46) | BTN3A1CARM1PRMT6HPGDALDH1A1 | |
| SCHEMBL16258631 | 0.88 | MEN1 (0.42) | BTN3A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16258629 | 0.88 | MEN1 (0.42) | BTN3A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL30583779 | 0.88 | MEN1 (0.42) | BTN3A1ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL16575733 | 0.87 | BTN3A1 (0.44) | BTN3A1HPGDALDH1A1TSHRKDM4E | |
| SCHEMBL29895522 | 0.84 | BTN3A1 (0.41) | BTN3A1HPGDALDH1A1TSHRKDM4E | |
| SCHEMBL28986476 | 0.84 | BTN3A1 (0.41) | BTN3A1HPGDALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805960-A1 | Methods for the preparation of diasteromerically pure phosphoramidate prodrugs | GILEAD SCIENCES, INC. (US) | 2014-11-26 | — | — | EP | disclosed |