Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.41 |
| ▸ | CCR3 | P51677 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30583779 | 1.00 | MEN1 (0.42) | MEN1KMT2ABTN3A1CCR3CA1 | |
| SCHEMBL16258629 | 1.00 | MEN1 (0.42) | MEN1KMT2ABTN3A1CCR3CA1 | |
| SCHEMBL30511498 | 0.91 | ALOX5 (0.41) | MEN1KMT2ABTN3A1CA1CA2 | |
| SCHEMBL17550480 | 0.90 | BTN3A1 (0.44) | MEN1KMT2ABTN3A1MAPTALDH1A1 | |
| SCHEMBL18476530 | 0.90 | ITGA4 (0.38) | MEN1KMT2ABTN3A1MAPTALDH1A1 | |
| SCHEMBL14934182 | 0.90 | ITGA4 (0.38) | MEN1KMT2ABTN3A1MAPTALDH1A1 | |
| SCHEMBL14934170 | 0.90 | ITGA4 (0.38) | MEN1KMT2ABTN3A1MAPTALDH1A1 | |
| SCHEMBL17550484 | 0.90 | BTN3A1 (0.40) | MEN1KMT2ABTN3A1CA1CA2 | |
| SCHEMBL17550481 | 0.89 | MEN1 (0.38) | MEN1KMT2ACCR3CA1CA2 | |
| SCHEMBL16015977 | 0.89 | BTN3A1 (0.49) | MEN1KMT2ABTN3A1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2805960-A1 | Methods for the preparation of diasteromerically pure phosphoramidate prodrugs | GILEAD SCIENCES, INC. (US) | 2014-11-26 | — | — | EP | disclosed |