Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670762 | 0.74 | LMNA (0.37) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL19595279 | 0.72 | ALDH1A1 (0.34) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL41691 | 0.72 | ALDH1A1 (0.40) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL16095310 | 0.72 | ALDH1A1 (0.38) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL1634068 | 0.72 | ALDH1A1 (0.34) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL5615220 | 0.71 | EPHX1 (0.42) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL22797 | 0.71 | — | — | |
| SCHEMBL5270433 | 0.71 | — | — | |
| SCHEMBL27669745 | 0.69 | ALDH1A1 (0.40) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 | |
| SCHEMBL10236415 | 0.69 | ALDH1A1 (0.43) | ALDH1A1RAB9AGAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809601-B1 | COMPOUNDS FOR ALZHEIMER'S DISEASE | MANFREDI JOHN (US) | 2014-09-10 | — | — | EP | disclosed |