SCHEMBL16016336

SCHEMBL16016336

NC(CCCCNC(=O)CCCc1ccc(I)cc1)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALB P02768 10/20 0.68
CA9 Q16790 1/20 0.52
LMNA P02545 2/20 0.49
PKM P14618 1/20 0.49
TSHR P16473 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
SLC5A1 P13866 1/20 0.46
TDP1 Q9NUW8 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19011014 1.00 ALB (0.68) ALBCA9LMNAPKMTSHR
SCHEMBL25499407 0.96 ALB (0.63) ALBCA9LMNAPKMTSHR
SCHEMBL19933090 0.94 ALB (0.60) ALBCA9LMNAL3MBTL1
SCHEMBL19924294 0.94 ALB (0.60) ALBCA9LMNAL3MBTL1
SCHEMBL30540749 0.91 ALB (0.60) ALBCA9LMNAPKML3MBTL1
SCHEMBL25499314 0.90 ALB (0.70) ALBCA9LMNAPKMTSHR
SCHEMBL25499308 0.89 ALB (0.69) ALBCA9LMNAPKMTSHR
SCHEMBL19924296 0.88 ALB (0.54) ALBCA9
SCHEMBL19924298 0.88 ALB (0.54) ALBCA9
SCHEMBL26548950 0.88 ALB (0.54) ALBCA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11939617-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2024-03-26 US claimed
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2023-10-19 US claimed
US-11214820-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2022-01-04 US claimed
WO-2018045376-A2 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IKARIA INC. (US) 2018-03-08 WO claimed
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2018-03-08 US claimed
US-11939617-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2024-03-26 US disclosed
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2023-10-19 US disclosed
US-11739076-B2 Compound or its salt thereof targeting fibroblast activation protein, its preparation methods and its uses thereof INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-08-29 US disclosed
US-11739076-B2 Compound or its salt thereof targeting fibroblast activation protein, its preparation methods and its uses thereof INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-08-29 US disclosed
US-20230159495-A1 COMPOUND OR ITS SALT THEREOF TARGETING FIBROBLAST ACTIVATION PROTEIN, ITS PREPARATION METHODS AND ITS USES THEREOF INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-05-25 US disclosed
US-20230159495-A1 COMPOUND OR ITS SALT THEREOF TARGETING FIBROBLAST ACTIVATION PROTEIN, ITS PREPARATION METHODS AND ITS USES THEREOF INSTITUTE OF NUCLEAR ENERGY RESEARCH ATOMIC ENERGY COUNCIL, R.O.C. (TW) 2023-05-25 US disclosed
WO-2022032353-A1 RADIOPHARMACEUTICALS, USES THEREOF, AND METHODS FOR THE PRODUCTION THEREOF Clarity Pharmaceuticals Ltd (AU) 2022-02-17 WO disclosed
US-20220009883-A1 THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF RATIO THERAPEUTICS, INC. 2022-01-13 US disclosed
US-11214820-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2022-01-04 US disclosed
US-20210009715-A1 NOVEL PSMA-BINDING AGENTS AND USES THEREOF LSI FINANCING LLC, AS ADMINISTRATIVE AGENT 2021-01-14 US disclosed
WO-2018045376-A2 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IKARIA INC. (US) 2018-03-08 WO disclosed
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2018-03-08 US disclosed
EP-2094647-B1 ALBUMIN BINDING MOLECULES AND USES THEREOF PHILOCHEM AG (CH) 2014-09-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210009715-A1 NOVEL PSMA-BINDING AGENTS AND USES THEREOF FOLH1, PSMA3, PSMA2 ALB 1845/4885CA9 128/4885LMNA 4549/4885
US-11739076-B2 Compound or its salt thereof targeting fibroblast activation protein, its preparation methods and its uses thereof FIBP, FGFR2, FGFR1 ALB 1815/4885CA9 2587/4885LMNA 2746/4885
US-11939617-B2 Functionally modified polypeptides and radiobiosynthesis IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885LMNA 2979/4885
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885LMNA 2979/4885
US-20220009883-A1 THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF ALB, TTR, ABCG2 ALB 1/4885CA9 702/4885LMNA 4231/4885
US-20230159495-A1 COMPOUND OR ITS SALT THEREOF TARGETING FIBROBLAST ACTIVATION PROTEIN, ITS PREPARATION METHODS AND ITS USES THEREOF FIBP, FGFR2, FGFR1 ALB 1815/4885CA9 2587/4885LMNA 2746/4885
US-11214820-B2 Functionally modified polypeptides and radiobiosynthesis IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885LMNA 2979/4885
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885LMNA 2979/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.