SCHEMBL19924296

SCHEMBL19924296

NC(CCCCNC(=S)CCCc1ccc(I)cc1)C(=O)O

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALB P02768 9/20 0.54
CA9 Q16790 2/20 0.42
FOLH1 Q04609 5/20 0.40
SIRT2 Q8IXJ6 2/20 0.39
SIRT1 Q96EB6 1/20 0.39
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
GRIK1 P39086 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19924298 1.00 ALB (0.54) ALBCA9FOLH1SIRT2SIRT1
SCHEMBL19933029 0.94 ALB (0.49) ALBCA9FOLH1CA12CA1
Trifluoroacetic Acid SCHEMBL30646991 0.94 ALB (0.48) ALBCA9FOLH1SIRT2SIRT1
SCHEMBL22021340 0.90 ALB (0.45) ALBFOLH1GRIK1
SCHEMBL22021341 0.89 ALB (0.46) ALBFOLH1
SCHEMBL22021344 0.88 PLAAT3 (0.48) ALBCA9SIRT2SIRT1CA12
SCHEMBL19929584 0.88 ALB (0.41) ALBCA9SIRT2SIRT1CA12
SCHEMBL26548495 0.88 ALB (0.41) ALBCA9FOLH1SIRT2SIRT1
SCHEMBL19929586 0.88 ALB (0.41) ALBCA9SIRT2SIRT1CA12
SCHEMBL26548503 0.88 ALB (0.41) ALBCA9SIRT2SIRT1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11939617-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2024-03-26 US claimed
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2023-10-19 US claimed
WO-2018045376-A2 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IKARIA INC. (US) 2018-03-08 WO claimed
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2018-03-08 US claimed
US-11939617-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2024-03-26 US disclosed
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2023-10-19 US disclosed
US-20220009883-A1 THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF RATIO THERAPEUTICS, INC. 2022-01-13 US disclosed
US-11214820-B2 Functionally modified polypeptides and radiobiosynthesis IKARIA INC. (US) 2022-01-04 US disclosed
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS RATIO THERAPEUTICS, INC. 2018-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11939617-B2 Functionally modified polypeptides and radiobiosynthesis IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885FOLH1 253/4885
US-20230332199-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885FOLH1 253/4885
US-20220009883-A1 THIOAMIDE-CONTAINING COMPOSITIONS AND METHODS OF USE THEREOF ALB, TTR, ABCG2 ALB 1/4885CA9 702/4885FOLH1 19/4885
US-11214820-B2 Functionally modified polypeptides and radiobiosynthesis IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885FOLH1 253/4885
US-20180066298-A1 FUNCTIONALLY MODIFIED POLYPEPTIDES AND RADIOBIOSYNTHESIS IL1RN, IL2RA, IL1A ALB 31/4885CA9 3993/4885FOLH1 253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.