SCHEMBL16016352

SCHEMBL16016352

C1=Cc2c(n(-c3cccc(-c4ccc(-c5ccc(-c6ccc(-n7c8ccccc8c8cnccc87)cc6)cn5)nc4)c3)c3ccccc23)CN1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 1/20 0.31
CDK6 Q00534 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16016383 0.94 MAOA (0.33) CDK4CDK6
SCHEMBL16016382 0.89 CDK4 (0.34) CDK4CDK6
SCHEMBL9921869 0.85 KDM4E (0.39) CDK4CDK6
SCHEMBL16016381 0.85 MAOA (0.32)
SCHEMBL16016440 0.83 MAOA (0.31)
SCHEMBL12919277 0.82 CDK4 (0.39) CDK4CDK6
SCHEMBL969757 0.82 MAOA (0.41)
SCHEMBL12919319 0.81 MAOA (0.38) CDK4CDK6
SCHEMBL16016429 0.79 MAOA (0.33) CDK4CDK6
SCHEMBL9921842 0.79 MAOA (0.39) CDK4CDK6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463288-B1 Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device HODOGAYA CHEMICAL CO LTD (JP) 2014-09-10 EP disclosed