Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10048449 | 0.89 | KARS1 (0.30) | KARS1 | |
| SCHEMBL13892803 | 0.85 | MAOA (0.31) | MAOAMAOBACHE | |
| SCHEMBL9922154 | 0.85 | MAOA (0.32) | MAOAMAOBACHEKARS1DDB1 | |
| SCHEMBL16016292 | 0.85 | MAOA (0.32) | MAOAMAOBACHEKARS1DDB1 | |
| SCHEMBL16016346 | 0.85 | HTR1A (0.33) | — | |
| SCHEMBL16016352 | 0.85 | CDK4 (0.31) | — | |
| SCHEMBL16016279 | 0.84 | MAOA (0.32) | MAOAMAOBACHEKARS1DDB1 | |
| SCHEMBL9921850 | 0.84 | MAOA (0.43) | MAOAMAOBACHEKARS1DDB1 | |
| SCHEMBL14706285 | 0.84 | MAOA (0.43) | MAOAMAOBACHEKARS1DDB1 | |
| SCHEMBL14706283 | 0.83 | MAOA (0.43) | MAOAMAOBACHEKARS1DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2241568-B1 | COMPOUND HAVING SUBSTITUTED PYRIDYL GROUP AND PYRIDOINDOLE RING STRUCTURE LINKED THROUGH PHENYLENE GROUP, AND ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2014-09-10 | — | — | EP | disclosed |