SCHEMBL16017484

SCHEMBL16017484

c1ccc([Si]2(c3ccccc3)c3ccccc3N(c3ccc(-n4c5ccccc5c5ccccc54)cn3)c3ccccc32)cc1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 1/20 0.32
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21008719 0.90 KDM4E (0.30) KDM4EATML3MBTL1
SCHEMBL21453574 0.83 MAOA (0.36) KDM4EATML3MBTL1
SCHEMBL21453575 0.83 CDK4 (0.36) KDM4EATML3MBTL1
SCHEMBL16017469 0.83 L3MBTL1 (0.50) KDM4EATML3MBTL1ALDH1A1PTPN1
SCHEMBL21453573 0.81 KDM4E (0.33) KDM4EATML3MBTL1
SCHEMBL14296799 0.79 L3MBTL1 (0.46) KDM4EATML3MBTL1ALDH1A1PTPN1
SCHEMBL21008720 0.78 HTT (0.31) KDM4E
SCHEMBL21008806 0.78 KDM4E (0.30) KDM4E
SCHEMBL16017468 0.78 KDM4E (0.34) KDM4EATML3MBTL1ALDH1A1
SCHEMBL21008718 0.78 KDM4E (0.31) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-8927749-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2015-01-06 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed
US-20140252318-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2014-09-11 US disclosed