Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28052529 | 1.00 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL11237591 | 0.89 | TBXAS1 (0.59) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL20272562 | 0.85 | PLA2G10 (0.50) | TBXAS1FFAR1NFKB1SMN1; SMN2PLA2G10 | |
| SCHEMBL11471957 | 0.85 | TBXAS1 (0.49) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL23643108 | 0.84 | EPHX1 (0.50) | ALOX5KDM4ESMN1; SMN2LOXL2TAAR1 | |
| SCHEMBL27780403 | 0.84 | KDM4E (0.46) | ESR1KDM4ESMN1; SMN2LOXL2SLC7A5 | |
| SCHEMBL12200630 | 0.84 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL15134789 | 0.84 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL15568884 | 0.84 | TBXAS1 (0.51) | TBXAS1FFAR1PTGS1PTGS2LMNA | |
| SCHEMBL19553694 | 0.83 | PTGS1 (0.66) | TBXAS1PTGS1PTGS2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140256912-A1 | Stabilized Variant MAML Peptides and Uses Thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256912-A1 | Stabilized Variant MAML Peptides and Uses Thereof | NOTCH1, MDN1, NOTCH2 | TBXAS1 3553/4885FFAR1 3653/4885PTGS1 4542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.