SCHEMBL16018767

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16016398	0.82	KMT2A (0.45)	POLBKMT2AMEN1CFTRMAPT
	SCHEMBL19225349	0.80	KMT2A (0.43)	POLBKMT2AMEN1CFTRMAPT
	SCHEMBL16018765	0.77	MPO (0.36)	POLBMAPTALDH1A1MPOSMN1; SMN2
	SCHEMBL16018770	0.76	SLC5A2 (0.46)	POLBKMT2AMEN1ALDH1A1MPO
	SCHEMBL16018764	0.75	MPO (0.36)	POLBKMT2AMEN1MPOCXCR2
	SCHEMBL19220559	0.75	MPO (0.37)	POLBMAPTMPOCTSASMN1; SMN2
	SCHEMBL16018768	0.73	SLC6A3 (0.40)	POLBALDH1A1MPOTDP1SMN1; SMN2
	SCHEMBL16018769	0.73	MPO (0.38)	MPOCXCR2HTR1BCX3CR1
	SCHEMBL16018772	0.73	MPO (0.35)	POLBKMT2AMEN1MPOCXCR2
	SCHEMBL16018762	0.72	GPER1 (0.41)	KDM4EMPOABL1CTSASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.