SCHEMBL160191

SCHEMBL160191

COC(=O)C(Cl)(Cl)OC

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL722674 0.75
SCHEMBL2007713 0.75 DGAT1 (0.42)
SCHEMBL20381160 0.74 DGAT1 (0.42)
SCHEMBL7842370 0.74
SCHEMBL9458300 0.74 ALDH1A1 (0.42)
SCHEMBL677960 0.73
SCHEMBL4305478 0.73 DGAT1 (0.46)
SCHEMBL6031180 0.73
SCHEMBL6065154 0.73
SCHEMBL7663104 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0967230-B1 Catalyst system for the preparation of olefin (co)polymers BAYER AG (DE) 2003-01-02 EP claimed
US-6180554-B1 ORGANOALUMINUM COMPOUND, GROUP IV-VI METAL COMPOUND, AND MONO-OR DIHALOCARBOXYLIC ACID ALKYL ESTER REACTIVATOR BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US claimed
EP-4719605-A1 CHEMICAL COMPOUNDS AND USES THEREOF GlaxoSmithKline Intellectual Property (No.4) Limited (GB) 2026-04-08 EP disclosed
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) 2026-01-15 US disclosed
US-12336981-B2 Compounds and compositions for the inhibition of NAMPT VALO HEALTH, INC. (US) 2025-06-24 US disclosed
WO-2024246862-A1 CHEMICAL COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 4) LIMITED (GB) 2024-12-05 WO disclosed
US-12064730-B2 Polymeric substrates with attached polymeric chains SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-08-20 US disclosed
EP-3728424-B1 POLYMERIC SUBSTRATES WITH ATTACHED THIOCARBONYLTHIO-CONTAINING GROUPS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2024-07-03 EP disclosed
US-20230346753-A1 NOVEL COMPOUNDS AND COMPOSITIONS FOR THE INHIBITION OF NAMPT VALO HEALTH, INC. 2023-11-02 US disclosed
CN-112020357-B Salt of indazolyl-containing tricyclic derivative and crystal form thereof 上海翰森生物医药科技有限公司 2023-08-29 CN disclosed
EP-3601390-B1 POLYMERIC MATERIALS FORMED USING CONTROLLED RADICAL INITIATORS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-05-03 EP disclosed
US-20050009829-A1 Benzimidazole-derivatives as factor Xa inhibitors AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2005-01-13 US disclosed
WO-2004101553-A1 BENZIMIDAZOLE-DERIVATIVES AS FACTOR Xa INHIBITORS SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) 2004-11-25 WO disclosed
EP-1479676-A1 Benzimidazole-derivatives as factor xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-11-24 EP disclosed
US-6180554-B1 ORGANOALUMINUM COMPOUND, GROUP IV-VI METAL COMPOUND, AND MONO-OR DIHALOCARBOXYLIC ACID ALKYL ESTER REACTIVATOR BAYER AKTIENGESELLSCHAFT (DE) 2001-01-30 US disclosed
JP-2000026517-A CATALYTIC SYSTEM FOR PRODUCING OLEFIN (CO)POLYMER BAYER AG 2000-01-25 JP disclosed
US-5194602-A 9α-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids GIST-BROCADES N.V. (NL) 1993-03-16 US disclosed
EP-0336521-B1 9-ALPHA-HYDROXY-17-METHYLENE STEROIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THE PREPARATION OF CORTICOSTEROIDS ROUSSEL-UCLAF (FR) 1992-04-01 EP disclosed
WO-1989009781-A1 9-ALPHA-HYDROXY-17-METHYLENE STEROIDS, THEIR PREPARATION AND UTILIZATION GIST-BROCADES N.V. (NL) 1989-10-19 WO disclosed
EP-0336521-A1 9-Alpha-hydroxy-17-methylene steroids, process for their preparation and their use in the preparation of corticosteroids ROUSSEL-UCLAF (FR) 1989-10-11 EP disclosed