Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16019755 | 0.90 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL16017065 | 0.86 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL13192768 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL20668745 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL595428 | 0.76 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL16019753 | 0.75 | TLR7 (0.47) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL14900243 | 0.74 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL19720176 | 0.73 | ALDH1A1 (0.39) | ALDH1A1KDM4EHPGDLMNANPSR1 | |
| SCHEMBL10272527 | 0.73 | PDE10A (0.32) | ADORA1 | |
| SCHEMBL11354287 | 0.73 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469614-B2 | Synthesis of triazolopyrimidine compounds | LEK PHARMACEUTICALS D.D. (SI) | 2016-10-18 | — | — | US | disclosed |
| US-20140256747-A1 | Synthesis of Triazolopyrimidine Compounds | LEK PHARMACEUTICALS D.D. (SI) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256747-A1 | Synthesis of Triazolopyrimidine Compounds | DPYD, TYMS, TYMP | ALDH1A1 1487/4885KDM4E 2840/4885HPGD 454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.