Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16019754 | 0.90 | ALDH1A1 (0.45) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL20668745 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL26975120 | 0.82 | HSP90AA1 (0.47) | LMNAKDM4EKMT2AGAAPDE10A | |
| SCHEMBL595428 | 0.81 | ALDH1A1 (0.48) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL13192768 | 0.79 | ALDH1A1 (0.43) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL16017065 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL11354287 | 0.77 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL13464342 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL29388389 | 0.76 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNAKDM4ENPSR1 | |
| SCHEMBL16063493 | 0.76 | ALDH1A1 (0.37) | ALDH1A1HPGDLMNAKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469614-B2 | Synthesis of triazolopyrimidine compounds | LEK PHARMACEUTICALS D.D. (SI) | 2016-10-18 | — | — | US | disclosed |
| US-9056838-B2 | Intermediates and processes for preparing Ticagrelor | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2015-06-16 | — | — | US | disclosed |
| US-20140256747-A1 | Synthesis of Triazolopyrimidine Compounds | LEK PHARMACEUTICALS D.D. (SI) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256747-A1 | Synthesis of Triazolopyrimidine Compounds | DPYD, TYMS, TYMP | ALDH1A1 1487/4885HPGD 454/4885LMNA 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.