⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL629180 | 0.86 | CA2 (0.38) | — | |
| SCHEMBL9765236 | 0.84 | CA2 (0.34) | — | |
| SCHEMBL1804507 | 0.80 | — | — | |
| Trifluoroacetic Acid SCHEMBL29481717 | 0.80 | ATR (0.36) | — | |
| SCHEMBL1805054 | 0.78 | — | — | |
| SCHEMBL1644673 | 0.76 | CA2 (0.46) | — | |
| SCHEMBL1869757 | 0.76 | CA2 (0.47) | — | |
| SCHEMBL9952155 | 0.76 | CA2 (0.47) | — | |
| SCHEMBL8632576 | 0.75 | CA2 (0.33) | — | |
| Sulfamide SCHEMBL27491894 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 696 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4007756-B1 | KIF18A INHIBITORS | AMGEN INC (US) | 2025-12-24 | — | — | EP | claimed |
| CN-120040345-A | KIF18A inhibitory activity small molecule compound, and pharmaceutical composition and application thereof | 皖南医学院第一附属医院（皖南医学院弋矶山医院） | 2025-05-27 | — | — | CN | claimed |
| CN-118666851-A | Condensed ring KIF18A inhibitor compound, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-09-20 | — | — | CN | claimed |
| CN-115295893-A | Aqueous zinc ion battery low-temperature electrolyte and additive thereof | 北京理工大学长三角研究院(嘉兴) | 2022-11-04 | — | — | CN | claimed |
| CN-114269731-A | KIF18A inhibitors | 美国安进公司 | 2022-04-01 | — | — | CN | claimed |
| EP-1780197-B9 | 5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2011-04-06 | — | — | EP | claimed |
| EP-1780197-B1 | 5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2010-10-20 | — | — | EP | claimed |
| US-7745663-B2 | 5-Substituted-2-phenylamino benzamides as MEK inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-06-29 | — | — | US | claimed |
| US-20090306126-A1 | Indole Derivatives | ASTRAZENECA AB (SE) | 2009-12-10 | — | — | US | claimed |
| US-20090233915-A1 | 5-Substituted-2-Phenylamino Benzamides as MEK Inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-09-17 | — | — | US | claimed |
| WO-2007129052-A1 | PYRAZOLE DERIVATIVES AND THEIR USE AS PI3K INHIBITORS | ASTRAZENECA AB (SE) | 2007-11-15 | — | — | WO | claimed |
| US-20070155933-A1 | Liquid polyethercarbonatediol compound and thermoplastic polyurethane obtained therefrom | UBE INDUSTRIES, LTD. (JP) | 2007-07-05 | — | — | US | claimed |
| EP-1430120-A4 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA | ALCON INC (CH) | 2007-06-20 | — | — | EP | claimed |
| EP-1780197-A1 | 5-SUBSTITUTED-2-PHENYLAMINO-BENZAMIDE AS MEK INHIBITOR | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-05-02 | — | — | EP | claimed |
| EP-1707586-A1 | LIQUID POLYETHER CARBONATE DIOL COMPOUND AND THERMOPLASTIC POLYURETHANE OBTAINED THEREFROM | Ube Industries, Ltd. (JP) | 2006-10-04 | — | — | EP | claimed |
| EP-1430120-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA | Alcon, Inc. (CH) | 2004-06-23 | — | — | EP | claimed |
| CN-1433408-A | Aminothiazole inhibitors of cyslin dependent kinases | BRISTOL MYERS SQUIBB CO (US) | 2003-07-30 | — | — | CN | claimed |
| WO-2003027275-A1 | INHIBITORS OF GLYCOGEN SYNTHASE KINASE-3 (GSK-3) FOR TREATING GLAUCOMA | ALCON, INC. (CH) | 2003-04-03 | — | — | WO | claimed |
| US-4454128-A | ANTIBIOTICS | DR. KARL THOMAE GMBH (DE) | 1984-06-12 | — | — | US | claimed |
| US-3943120-A | WATER INSOLUBLE | CIBA-GEIGY AG (CH) | 1976-03-09 | — | — | US | claimed |