Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16021748 | 0.85 | CHKA (0.46) | CHKADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL16024121 | 0.81 | CHKA (0.48) | CHKADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL15220294 | 0.81 | DRD2 (0.58) | CHKADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL21291349 | 0.80 | CHKA (0.47) | CHKADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL11487020 | 0.78 | DRD4 (0.45) | DRD2DRD4DRD3CYP1A2CYP3A4 | |
| SCHEMBL21695408 | 0.77 | RARB (0.49) | CHKADRD2DRD4DRD3CYP3A4 | |
| SCHEMBL6342735 | 0.77 | NQO1 (0.58) | CHKAMAOBMEN1KMT2A | |
| SCHEMBL14173682 | 0.76 | NR1I2 (0.49) | CHKADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL14832975 | 0.76 | DRD4 (0.44) | CHKADRD2DRD4DRD3CYP1A2 | |
| SCHEMBL29324799 | 0.75 | KMT2A (0.51) | HPGDMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-10556912-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2020-02-11 | — | — | US | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | CHKA 1726/4885HPGD 836/4885DRD2 417/4885 |
| US-10556912-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | CHKA 1726/4885HPGD 836/4885DRD2 417/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | CHKA 1726/4885HPGD 836/4885DRD2 417/4885 |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | CHKA 1726/4885HPGD 836/4885DRD2 417/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | CHKA 1726/4885HPGD 836/4885DRD2 417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.