Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18562058 | 0.85 | ALDH1A1 (0.45) | CASP1TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL28308098 | 0.84 | ALDH1A1 (0.46) | CASP1TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL97154 | 0.79 | TSHR (0.44) | TSHRALDH1A1MAPTGAALMNA | |
| SCHEMBL7290933 | 0.79 | ALDH1A1 (0.36) | CASP1TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL2624853 | 0.78 | ALDH1A1 (0.44) | CASP1TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL28342821 | 0.76 | CYP3A4 (0.42) | TSHRALDH1A1CYP3A4LMNAHPGD | |
| SCHEMBL26363682 | 0.76 | ALDH1A1 (0.34) | ALDH1A1CYP3A4MAPTKDM4ELMNA | |
| Benzene SCHEMBL28104497 | 0.76 | TSHR (0.46) | TSHRALDH1A1KDM4EGAALMNA | |
| SCHEMBL16574317 | 0.76 | MAOB (0.41) | CASP1TSHRALDH1A1CYP3A4RECQL | |
| SCHEMBL27792581 | 0.76 | FFAR1 (0.41) | ALDH1A1MAPTKDM4EHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9782406-B2 | Kinase inhibitor and method for treatment of related diseases | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2017-10-10 | — | — | US | disclosed |
| EP-1561743-B1 | COMPOUND PROTECTING AGAINST ULTRAVIOLET | LEAD CHEM CO LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20150352109-A1 | KINASE INHIBITOR AND METHOD FOR TREATMENT OF RELATED DISEASES | BEIJING RECIPROCAPHARMACEUTICALS CO. LTD. (CN) | 2015-12-10 | — | — | US | disclosed |
| US-9150522-B2 | Kinase inhibitor and method for treatment of related diseases | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2015-10-06 | — | — | US | disclosed |
| US-20140256759-A1 | KINASE INHIBITOR AND METHOD FOR TREATMENT OF RELATED DISEASES | PEKING UNIVERSITY SHENZHEN GRADUATE SCHOOL (CN) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140256759-A1 | KINASE INHIBITOR AND METHOD FOR TREATMENT OF RELATED DISEASES | BTK, TYK2, JAK2 | CASP1 1506/4885TSHR 1535/4885ALDH1A1 4751/4885 |
| US-20150352109-A1 | KINASE INHIBITOR AND METHOD FOR TREATMENT OF RELATED DISEASES | BTK, TYK2, JAK2 | CASP1 1506/4885TSHR 1535/4885ALDH1A1 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.